Clinical Trials

Phase 3 Not yet recruiting

Biliary Tract Neoplasms

NCT07582315 2026-05-22

A Study Comparing BL-B01D1 With Treatment of Physician's Choice in Patients With Locally Advanced or Metastatic Biliary Tract Cancer After Failure of Platinum-based Chemotherapy and PD-1/PD-L1 Monoclonal Antibody Therapy(PANKU-BTC01)

538 enrolled

Phase 3 Not yet recruiting

Biliary Tract Neoplasms

NCT06622057 2026-04-14

D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer

195 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT05849480 2026-03-24

A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)

Phase 1/2 Recruiting

60 enrolled

GastrointestinalGynecologic

Bile Duct Neoplasms, Biliary Tract Neoplasms

NCT05489211 2026-03-19

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

Phase 2 Recruiting

454 enrolled

Biliary Tract Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT06109779 2026-03-04

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

Phase 3 Active not recruiting

757 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT06065371 2025-12-19

Sacituzumab Govitecan in Combination With Capecitabine for Advanced Gastrointestinal Cancers After Progression on Standard Therapy

Phase 1 Recruiting

20 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05482893 2025-11-04

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

Phase 1/2 Recruiting

258 enrolled

Biliary Tract Neoplasms

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT07156058 2025-09-04

MiniPDX-based Postoperative Adjuvant Therapy for Biliary Tract Cancer

Phase NA Recruiting

204 enrolled

Biliary Tract Neoplasms

NCT05239169 2025-05-01

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

40 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05065957 2025-04-30

Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer

Phase 2/3 Recruiting

180 enrolled

Biliary Tract Neoplasms

NCT06037980 2025-02-17

PURITY

Phase 2/3 Recruiting

300 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT04720131 2024-01-30

Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.

28 enrolled

Biliary Tract Neoplasms

NCT03079427 2022-12-06

Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic Cholangiocarcinoma

101 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma

NCT04401709 2022-06-15

Gemcitabine+ Capecitabine Vs Capecitabine in Curatively Resected Biliary Tract Cancer

Phase 3 Unknown

490 enrolled

Biliary Tract Neoplasms

NCT04608786 2022-01-11

A Clinical Study of PD-L1 Antibody ZKAB001 Combined With Capecitabine in Resected Biliary Tract Cancer

Phase 1 Unknown

10 enrolled

Biliary Tract Neoplasms

NCT03111732 2021-12-03

Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC)

11 enrolled 16 charts

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Liver Neoplasms, Cholangiocarcinoma

NCT03093870 2021-08-03

TreeTopp

Phase 2/3 Completed

151 enrolled 18 charts

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms, Neoplasms

NCT03231176 2020-11-19

Varlitinib Plus Capecitabine in Chinese Patients With Advanced or Metastatic Biliary Tract Cancer

62 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Gallbladder Neoplasms

NCT03873532 2020-02-13

A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma Patients

Phase 2/3 Unknown

298 enrolled

Biliary Tract Neoplasms

NCT02773459 2019-09-30

MEK162 in Combination With Capecitabine in Advanced Biliary Tract Cancer

Phase 1/2 Completed

31 enrolled

Biliary Tract Neoplasms

NCT02350686 2019-05-20

XELOX in Advanced Biliary Tract Carcinoma After Failure of Gemcitabine-based Chemotherapy

Phase 2 Unknown

67 enrolled

Biliary Tract Neoplasms

NCT03609489 2018-08-09

A Study to Investigate Apatinib Combined Capecitabine on Adjuvant Therapy of Biliary Carcinoma

Phase 2 Unknown

40 enrolled

Biliary Tract Neoplasms

NCT03082053 2018-06-28

A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours

24 enrolled

Biliary Tract Neoplasms

NCT03129074 2018-05-23

Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer

Phase 2 Withdrawn

Biliary Tract Neoplasms

NCT00142480 2018-04-25

Capecitabine, Oxaliplatin, Bevacizumab and Radiation Therapy in Patients With Biliary Tract and Gallbladder Cancer

8 enrolled

Biliary Tract Neoplasms

NCT02558959 2018-02-13

Second-line Irinotecan and Capecitabine Versus Irinotecan for Gemcitabine and Cisplatin Refractory Biliary Tract Cancer

64 enrolled

Biliary Tract Neoplasms

NCT01843725 2018-01-31

MOMENTUM1

37 enrolled

BreastGastrointestinal

Biliary Tract Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT02720601 2018-01-25

Irinotecan and Capecitabine as Second-line Treatment for Advanced/Metastatic Biliary Tract Cancers

Phase 2 Withdrawn

Biliary Tract Neoplasms, Gallbladder Neoplasms

NCT01572324 2017-01-04

Study of Hepatic Arterial Infusion to Treat Biliary Tract Carcinomas

37 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT00868998 2016-05-23

GTX Regimen for Biliary Cancers

Phase 2 Terminated

4 enrolled 7 charts

Biliary Tract Neoplasms

NCT01530503 2016-02-25

BIT-2

52 enrolled

Biliary Tract Neoplasms

NCT00630890 2015-09-11

Cyberknife Radiosurgery Boost for Hilar Cholangiocarcinoma (Klatskin Tumor)

Phase 1 Terminated

11 enrolled

Biliary Tract Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT00551096 2013-12-25

Gemcitabine/Capecitabine/ZD6474 in Advanced Solid Tumors

23 enrolled

Biliary Tract Neoplasms, Pancreatic Neoplasms

NCT00338988 2012-08-01

Oxaliplatin and Capecitabine in Patients With Unresectable Cholangiocarcinoma

44 enrolled 5 charts

Biliary Tract Neoplasms, Gallbladder Neoplasms

NCT00626158 2012-04-04

Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers

45 enrolled