Clinical Trials

120 enrolled

BreastGastrointestinal

Biliary Tract Neoplasms, Breast Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT07101874 2026-03-27

ARCBile

730 enrolled

Biliary Tract Neoplasms

NCT02829918 2026-03-11

Study of Nivolumab in Patients With Advanced Refractory Biliary Tract Cancers

54 enrolled 11 charts

Biliary Tract Neoplasms, Digestive System Diseases

NCT07184047 2026-02-20

TOX-FRAIL

72 enrolled

Frailty, Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Malnutrition, Sarcopenia, Sarcoglycanopathies

NCT03785873 2026-02-13

Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer

34 enrolled 13 charts

Biliary Tract Neoplasms

NCT05512377 2026-01-21

Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder

GastrointestinalGenitourinaryThoracic

99 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Lung Neoplasms, Pancreatic Neoplasms

NCT05254847 2026-01-20

Capecitabine Combined With Lenvatinib and Tislelizumab as Adjuvant Treatment After Resection in Patients With BTC

65 enrolled

Biliary Tract Neoplasms

NCT05835778 2026-01-14

Imfinzi BTC Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - CEI/SCEI

236 enrolled

Biliary Tract Neoplasms

NCT04896931 2026-01-07

New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma (PERSUASION)- a Permanent Platform Including All Kind of Biliary Tract Cancers (BTC)

159 enrolled

Biliary Tract Neoplasms

NCT07252570 2025-11-26

Portal Vein Stenting for Malignant Obstruction: Feasibility, Safety, and Clinical Outcomes

63 enrolled

Biliary Tract Neoplasms, Hypertension, Portal, Pancreatic Neoplasms

NCT03797326 2025-11-17

LEAP-005

BreastCNSGastrointestinalGynecologic

611 enrolled 27 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Biliary Tract Neoplasms, Glioblastoma, Ovarian Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT04068168 2025-11-17

Imfinzi PMS

712 enrolled

GastrointestinalThoracic

Biliary Tract Neoplasms, Lung Neoplasms

NCT02576431 2025-11-12

NAVIGATE

BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

215 enrolled 5 FDA

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT03044587 2025-10-01

NIFE

93 enrolled

Bile Duct Neoplasms, Biliary Tract Neoplasms, Cholangiocarcinoma

NCT05052099 2025-09-29

COMBATBIL

20 enrolled

Biliary Tract Neoplasms

NCT04466891 2025-09-15

HERIZON-BTC-01

87 enrolled 25 charts 3 FDA

Biliary Tract Neoplasms, Gallbladder Neoplasms

NCT05429203 2025-09-15

Comparison of Duodenoscope With Single-use Distal Cover and the Conventional Reusable Duodenoscope

319 enrolled 21 charts

Biliary Tract Neoplasms, Gallbladder Diseases, Pancreatic Diseases, Pancreatic Neoplasms, Choledocholithiasis

NCT03929666 2025-09-12

A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer

74 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT00924027 2025-09-05

A Study of Patients Receiving High-Dose Rate Brachytherapy

GastrointestinalGenitourinaryGynecologic

43 enrolled 13 charts

Biliary Tract Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Neoplasms, Prostatic Neoplasms, Endometrial Neoplasms

NCT05044065 2025-08-27

PREV-Ex

52 enrolled

Biliary Tract Neoplasms, Liver Neoplasms, Pancreatic Neoplasms

NCT04871321 2025-08-26

Biomarker Discovery in Patients With Advanced Biliary Tract Cancer

119 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT03314935 2025-08-12

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

GastrointestinalGynecologic

149 enrolled 35 charts

Biliary Tract Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms

NCT05253053 2025-06-12

To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckThoracic

84 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Gallbladder Neoplasms, Prostatic Neoplasms, Stomach Neoplasms, Thyroid Neoplasms, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03639935 2025-06-03

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy

32 enrolled 14 charts

Biliary Tract Neoplasms, Neoplasm Metastasis

NCT06960733 2025-05-07

Comparison Between Winged Versus Traditional Plastic Stents for Biliary Drainage

21 enrolled

Biliary Tract Neoplasms, Cholecystolithiasis

NCT05239169 2025-05-01

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

40 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma, Klatskin Tumor

NCT05924880 2025-04-22

TopDouble

Phase 3 Completed

116 enrolled

Biliary Tract Neoplasms

NCT04566614 2025-04-06

PREVAILctDNA

GastrointestinalGenitourinaryThoracic

128 enrolled

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT04907851 2025-03-17

KEYNOTE-E86

45 enrolled 25 charts

Biliary Tract Neoplasms, Pancreatic Neoplasms, Cholangiocarcinoma

NCT03447470 2025-01-29

Study to Evaluate the Safety and Tolerability of RXC004 in Advanced Malignancies

46 enrolled 29 charts

Biliary Tract Neoplasms, Neoplasms, Thymus Neoplasms

NCT05462314 2025-01-28

Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies

24 enrolled

Biliary Tract Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Liver Neoplasms, Neoplasm Metastasis, Pancreatic Neoplasms, Rectal Neoplasms, Stomach Neoplasms

NCT04338685 2024-12-09

A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases

55 enrolled 30 charts

Biliary Tract Neoplasms, Carcinoma, Hepatocellular

NCT05712889 2024-11-15

Phase 1 Dose Escalation Study for VIP236 in Patients With Advanced Cancer

BreastGastrointestinalGynecologicThoracic

29 enrolled

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Stomach Neoplasms, Endometrial Neoplasms, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT03673072 2024-11-12

GAIN

Phase 3 Completed

68 enrolled

Biliary Tract Neoplasms

NCT02443324 2024-07-31

A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer

GastrointestinalGenitourinaryThoracic

175 enrolled 23 charts

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Ureteral Neoplasms, Urethral Neoplasms

NCT02091141 2024-07-23

My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors

GastrointestinalGenitourinary

673 enrolled 22 charts

Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Neoplasms

NCT04677504 2024-07-03

A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract Cancer

162 enrolled 18 charts

Biliary Tract Neoplasms

NCT04595058 2024-04-18

BAMPI

123 enrolled

Biliary Tract Neoplasms, Pancreatic Neoplasms

NCT04720131 2024-01-30

Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.

28 enrolled

Biliary Tract Neoplasms

NCT05074472 2024-01-29

A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors

GastrointestinalGynecologic

35 enrolled

Adenocarcinoma, Biliary Tract Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms

NCT06222619 2024-01-25

Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar Cholangiocarcinoma

136 enrolled

Biliary Tract Neoplasms

NCT03230318 2023-12-19

FIDES-01

148 enrolled 15 charts

Bile Duct Neoplasms, Biliary Tract Neoplasms, Liver Neoplasms, Cholangiocarcinoma

NCT03796429 2023-11-29

A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer

50 enrolled

Biliary Tract Neoplasms

NCT03531320 2023-11-24

Study of D07001-Softgel Capsules in Subjects With Gastrointestinal Cancer in Dose-Escalation Phase and in Subjects With Biliary Tract Cancer in Dose-Expansion Phase

19 enrolled 13 charts

Biliary Tract Neoplasms, Gastrointestinal Neoplasms

NCT03260712 2023-11-03

Pembrolizumab in Biliary Tract Cancer

50 enrolled

Biliary Tract Neoplasms, Gallbladder Neoplasms, Neoplasm Metastasis

NCT03833661 2023-10-25

M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)

159 enrolled 23 charts

Biliary Tract Neoplasms, Camurati-Engelmann Syndrome, Gallbladder Neoplasms, Cholangiocarcinoma

NCT04722133 2023-10-11

Trastuzumab-pkrb Combined With Modified FOLFOX-6 in Biliary Tract Cancer Patients Progressed on First Line Therapy

36 enrolled

Biliary Tract Neoplasms

NCT02866383 2023-09-22

CheckPAC

160 enrolled