Announcements Trials
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Phase

Phase 2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Myeloid 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Leukemia, Myeloid, Acute 3Sarcoma 2Rhabdomyosarcoma 2Myelodysplastic Syndromes 2Leukemia, Biphenotypic, Acute 2Ganglioneuroblastoma 2Sarcoma, Myeloid 1Recurrence 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pleuropulmonary blastoma 1PRETEXT I Hepatoblastoma 1Neuroblastoma 1Neoplasm Metastasis 1Myeloproliferative Disorders 1Malignant mesenchymal tumor 1Lymphoma, Large B-Cell, Diffuse 1Localized Extraskeletal Ewing Sarcoma 1Leukemia 1Heart Failure 1Drug-Related Side Effects and Adverse Reactions 1Dendritic Cell Sarcoma, Interdigitating 1Degradation of Top2b and Top2a in Human by Dexrazoxane 1Cardiotoxicity 1Burkitt Lymphoma 1Blast Crisis 1

Interventions

Methotrexate 6Cyclophosphamide 6ponatinib 5Cytarabine 5merphos 4Mycophenolic Acid 4blinatumomab 3Whole-Body Irradiation 3Tacrolimus 3Peripheral Blood Stem Cell Transplantation 3Cyclosporine 3venetoclax 2fludarabine phosphate 2bosutinib 2Vincristine 2Rituximab 2N,N-dicyclohexyl-isoborneol-10-sulfonamide 2Idarubicin 2Etoposide 2Cladribine 2CT-P10 2Busulfan 2prednylidene 1pegfilgrastim 1nilotinib 1midostaurin 1gilteritinib 1fludarabine 1dexamethasone acetate 1dexamethasone 21-phosphate 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Blast Crisis × Dexrazoxane × 1 year × Clear all
NCT03589729 2026-05-22

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

M.D. Anderson Cancer Center

Phase 2 Recruiting
100 enrolled
MyeloidOther hematologic neoplasmSarcoma

Blast Crisis, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Sarcoma, Myeloid

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