Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Terminated 1Recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2Other hematologic neoplasm 2Myeloid 1Lymphoid 1Dermatologic 1

Conditions

Sarcoma 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Cardiotoxicity 8Osteosarcoma 5Recurrence 4Rhabdomyosarcoma 3Neuroectodermal Tumors, Primitive, Peripheral 3Neuroblastoma 3Lymphoma 3Leukemia, Myeloid, Acute 3Leukemia, Biphenotypic, Acute 3Leukemia 3Breast Neoplasms 3Sarcoma, Ewing 2Myelodysplastic Syndromes 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Large B-Cell, Diffuse 2Ganglioneuroblastoma 2Dendritic Cell Sarcoma, Interdigitating 2Burkitt Lymphoma 2Blast Crisis 2Vomiting 1Unspecified Adult Solid Tumor, Protocol Specific 1Sezary Syndrome 1Sarcoma, Synovial 1Sarcoma, Myeloid 1Rhabdoid Tumor 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pleuropulmonary blastoma 1PRETEXT I Hepatoblastoma 1

Interventions

Cyclophosphamide 64Peripheral Blood Stem Cell Transplantation 57fludarabine phosphate 54Busulfan 43Tacrolimus 38Methotrexate 38Cytarabine 36Filgrastim 34Cyclosporine 33Mycophenolic Acid 32Antilymphocyte Serum 32Whole-Body Irradiation 27Radiotherapy 25Methylprednisolone 22Imatinib Mesylate 22Etoposide 22Melphalan 18Cord Blood Stem Cell Transplantation 17Thiotepa 12Dasatinib 12Flow Cytometry 11sargramostim 10merphos 10fludarabine 10Sirolimus 10Granulocyte Colony-Stimulating Factor 10Therapeutics 9Prednisone 9Decitabine 9Carboplatin 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Interventional × Blast Crisis × Dexrazoxane × Clear all
NCT03589729 2026-05-22

Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers

M.D. Anderson Cancer Center

Phase 2 Recruiting
100 enrolled
MyeloidOther hematologic neoplasmSarcoma

Blast Crisis, Myeloproliferative Disorders, Leukemia, Myeloid, Acute, Sarcoma, Myeloid

NCT00933985 2014-05-01

Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
22 enrolled
DermatologicLymphoidOther hematologic neoplasmSarcoma

Blast Crisis, Burkitt Lymphoma, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Mycosis Fungoides, Recurrence, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating, Intraocular Lymphoma

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