Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Plasma cell 1Myeloid 1Lymphoid 1Classical hematology 1

Conditions

Breast Neoplasms 10Carcinoma, Non-Small-Cell Lung 5Precursor Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Breast Diseases 4Thoracic Neoplasms 3Respiratory Tract Neoplasms 3Pancreatic Neoplasms 3Lung Neoplasms 3Lung Diseases 3Leukemia, Myeloid, Acute 3Bronchial Neoplasms 3Sezary Syndrome 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Pinealoma 2Neoplasms, Glandular and Epithelial 2Neoplasms by Histologic Type 2Myelodysplastic Syndromes 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Lymphoma, Large-Cell, Immunoblastic 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, Large B-Cell, Diffuse 2Lymphoma, Follicular 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma 2Leukemia, Myelomonocytic, Chronic 2Leukemia, Lymphocytic, Chronic, B-Cell 2

Interventions

Cytarabine 11Cyclophosphamide 10Filgrastim 9Etoposide 8fludarabine phosphate 6Vorinostat 6Tacrolimus 6Peripheral Blood Stem Cell Transplantation 6Imatinib Mesylate 6Dasatinib 6Carboplatin 5tipifarnib 4sargramostim 4Topotecan 4Sirolimus 4Bortezomib 4tanespimycin 3fludarabine 3alvocidib 3Whole-Body Irradiation 3Sorafenib 3Flow Cytometry 3Doxorubicin 3Decitabine 3Busulfan 3Antilymphocyte Serum 33-aminopyridine-2-carboxaldehyde thiosemicarbazone 3laromustine 2entinostat 2bryostatin 1 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Blast Crisis × entinostat × Clear all
NCT01159301 2013-09-19

Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
44 enrolled
Other hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT00015925 2010-03-10

MS-275 in Treating Patients With Hematologic Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Phase 1 Completed
Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Blast Crisis, Leukemia, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative

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