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Phase

Phase 2 2Phase 1/2 1Phase 1 1

Status

Terminated 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Myeloid 1Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 55Myelodysplastic Syndromes 19Recurrence 18Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Leukemia, Lymphocytic, Chronic, B-Cell 13Leukemia, Myelomonocytic, Chronic 12Lymphoma, Non-Hodgkin 11Leukemia 11Multiple Myeloma 9Lymphoma, Mantle-Cell 7Hematologic Neoplasms 7Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, Follicular 6Lymphoma 6Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 5Lymphoma, Large B-Cell, Diffuse 5Leukemia, Myeloid 3Burkitt Lymphoma 3Neoplasms 2Neoplasm, Residual 2Myeloproliferative Disorders 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma, B-Cell 2Leukemia, Prolymphocytic, T-Cell 2Leukemia, Biphenotypic, Acute 2Immunoglobulin Light-chain Amyloidosis 2Dendritic Cell Sarcoma, Interdigitating 2Waldenstrom Macroglobulinemia 1Thrombocytosis 1Thrombocythemia, Essential 1

Interventions

Peripheral Blood Stem Cell Transplantation 13Tacrolimus 7Busulfan 7fludarabine phosphate 6Mycophenolic Acid 6Methotrexate 6Imatinib Mesylate 6Cyclosporine 6Filgrastim 5Cyclophosphamide 5Whole-Body Irradiation 3Decitabine 3Cytarabine 3ponatinib 2nilotinib 2bosutinib 2aldesleukin 2Thiotepa 2Stem Cell Transplantation 2Radiotherapy 2Melphalan 2Flow Cytometry 2Etoposide 2Cord Blood Stem Cell Transplantation 2Blood Specimen Collection 2Arsenic Trioxide 2Antilymphocyte Serum 2venetoclax 1vatalanib 1ruxolitinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Blast Crisis × venetoclax × Clear all
NCT03576547 2025-05-08

Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia

M.D. Anderson Cancer Center

Phase 1/2 Terminated
9 enrolled 11 charts
LymphoidMyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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