Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Recruiting 2Completed 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Myeloid 3Other hematologic neoplasm 2Lymphoid 2

Conditions

Multiple Myeloma 420Precursor Cell Lymphoblastic Leukemia-Lymphoma 126Neoplasms, Plasma Cell 74Recurrence 70Lymphoma 57Leukemia 54Neoplasms 46Immunoglobulin Light-chain Amyloidosis 38Burkitt Lymphoma 37Vomiting 36Lymphoma, Mantle-Cell 32Lymphoma, Large B-Cell, Diffuse 31Nausea 29Lymphoma, Non-Hodgkin 28Breast Neoplasms 22Waldenstrom Macroglobulinemia 21Lymphoma, Follicular 21Hodgkin Disease 21Leukemia, Lymphocytic, Chronic, B-Cell 20Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 17Neoplasm Metastasis 17Prostatic Neoplasms 16Lymphoma, Extranodal NK-T-Cell 16Amyloidosis 16Leukemia, Myeloid, Acute 15Smoldering Multiple Myeloma 14Lymphoma, B-Cell, Marginal Zone 13Lung Neoplasms 11Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 10Lymphoma, B-Cell 10

Interventions

Cyclophosphamide 7fludarabine phosphate 6venetoclax 5tagraxofusp 5Whole-Body Irradiation 4Mycophenolic Acid 4Methotrexate 4fludarabine 3Thiotepa 3Dexamethasone 3Cyclosporine 3Calcium Dobesilate 3merphos 2dexamethasone acetate 2dexamethasone 21-phosphate 2auricularum 2Vincristine 2Tacrolimus 2Specimen Handling 2Rituximab 2Peripheral Blood Stem Cell Transplantation 2Cytarabine 2Cyclosporins 2Azacitidine 2prednylidene 1lorvotuzumab mertansine 1exifone 1deltacortene 1azathiopurine 1X-Rays 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Blastic Plasmacytoid Dendritic Cell Neoplasm × Dexamethasone × Clear all
NCT04216524 2026-04-14

Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

M.D. Anderson Cancer Center

Phase 2 Recruiting
40 enrolled
Myeloid

Blastic Plasmacytoid Dendritic Cell Neoplasm

NCT04681105 2026-01-28

Flotetuzumab for the Treatment of Relapsed or Refractory Advanced CD123-Positive Hematological Malignancies

City of Hope Medical Center

Phase 1 Completed
13 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Hairy Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Hematologic Neoplasms, Mastocytosis, Systemic, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05476770 2024-12-06

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1 Recruiting
54 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hodgkin Disease, Leukemia, Biphenotypic, Acute, Lymphoma, B-Cell, Lymphoma, T-Cell, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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