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Phase

Phase 2 3Phase 1 2Phase NA 1Phase 1/2 1

Status

Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 2

Conditions

Leukemia, Myeloid, Acute 55Precursor Cell Lymphoblastic Leukemia-Lymphoma 45Myelodysplastic Syndromes 42Leukemia, Lymphocytic, Chronic, B-Cell 40Leukemia 38Lymphoma, Non-Hodgkin 32Multiple Myeloma 31Lymphoma 31Lymphoma, Mantle-Cell 26Lymphoma, Follicular 24Lymphoma, Large B-Cell, Diffuse 23Hodgkin Disease 22Melanoma 21Burkitt Lymphoma 19Lymphoma, B-Cell, Marginal Zone 18Leukemia, Myelomonocytic, Chronic 17Recurrence 14Anemia, Refractory, with Excess of Blasts 14Congenital Abnormalities 13Neoplasms, Plasma Cell 12Myeloproliferative Disorders 12Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 11Lymphoma, Large-Cell, Immunoblastic 11Hematologic Neoplasms 11Leukemia, Myeloid, Chronic-Phase 10Primary Myelofibrosis 9Lymphoma, Large-Cell, Anaplastic 9Lymphoma, B-Cell 9Leukemia, Myelogenous, Chronic, BCR-ABL Positive 9Ovarian Neoplasms 8

Interventions

fludarabine 3venetoclax 2tagraxofusp 2fludarabine phosphate 2Dexamethasone 2Cytarabine 2Cyclophosphamide 2Calcium Dobesilate 2Azacitidine 2dexamethasone acetate 1dexamethasone 21-phosphate 1auricularum 1Vincristine 1Specimen Handling 1Rituximab 1Ranitidine 1Methotrexate 1Mesna 1Magnetic Resonance Spectroscopy 1MK 2206 1Ibuprofen 1Hydrocortisone 1Diphenhydramine 1Biopsy 1Acetaminophen 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Blastic Plasmacytoid Dendritic Cell Neoplasm × fludarabine phosphate × Clear all
NCT04318678 2026-05-19

CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)

St. Jude Children's Research Hospital

Phase 1 Recruiting
108 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02159495 2025-09-16

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

City of Hope Medical Center

Phase 1 Active not recruiting
31 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Neoplasm, Residual, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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