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Phase

Phase 2 3Phase 1 2Phase 1/2 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Myeloid 2Lymphoid 1

Conditions

Leukemia, Myeloid, Acute 4Myelodysplastic Syndromes 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Primary Myelofibrosis 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Lymphoma, T-Cell 1Lymphoma, B-Cell 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Biphenotypic, Acute 1Hodgkin Disease 1Hematologic Neoplasms 1

Interventions

fludarabine 3venetoclax 2tagraxofusp 2fludarabine phosphate 2Dexamethasone 2Cytarabine 2Cyclophosphamide 2Calcium Dobesilate 2Azacitidine 2dexamethasone acetate 1dexamethasone 21-phosphate 1auricularum 1Vincristine 1Specimen Handling 1Rituximab 1Ranitidine 1Methotrexate 1Mesna 1Magnetic Resonance Spectroscopy 1MK 2206 1Ibuprofen 1Hydrocortisone 1Diphenhydramine 1Biopsy 1Acetaminophen 1AP 1903 reagent 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Blastic Plasmacytoid Dendritic Cell Neoplasm × tagraxofusp × Clear all
NCT03113643 2025-11-04

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Dana-Farber Cancer Institute

Phase 1 Recruiting
72 enrolled
MyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05476770 2024-12-06

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Therapeutic Advances in Childhood Leukemia Consortium

Phase 1 Recruiting
54 enrolled
LymphoidMyeloidOther hematologic neoplasm

Blastic Plasmacytoid Dendritic Cell Neoplasm, Hodgkin Disease, Leukemia, Biphenotypic, Acute, Lymphoma, B-Cell, Lymphoma, T-Cell, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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