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Phase

Phase 1 3Phase 2 1Phase 1/2 1

Status

Completed 4Recruiting 1Not yet recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Myeloid 1Classical hematology 1

Conditions

Carcinoma, Non-Small-Cell Lung 156Neoplasms 115Colorectal Neoplasms 98Breast Neoplasms 93Pancreatic Neoplasms 81Neoplasm Metastasis 81Leukemia, Myeloid, Acute 79Recurrence 76Prostatic Neoplasms 74Ovarian Neoplasms 74Melanoma 74Multiple Myeloma 66Stomach Neoplasms 59Lung Neoplasms 56Squamous Cell Carcinoma of Head and Neck 55Triple Negative Breast Neoplasms 50Glioblastoma 49Lymphoma 47Endometrial Neoplasms 43Carcinoma, Hepatocellular 42Advanced Solid Tumor 42Lymphoma, Non-Hodgkin 41Precursor Cell Lymphoblastic Leukemia-Lymphoma 40Advanced Solid Tumors 37Small Cell Lung Carcinoma 35Uterine Cervical Neoplasms 34Carcinoma, Renal Cell 34Lymphoma, Large B-Cell, Diffuse 32Lymphoma, B-Cell 32Sarcoma 30

Interventions

11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1/2 × Recruiting × Bone Marrow Diseases × Clear all
NCT06303193 2026-06-05

Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
160 enrolled
Classical hematologyMyeloid

Anemia, Aplastic, Anemia, Refractory, with Excess of Blasts, Bone Marrow Diseases, Myelodysplastic Syndromes, Myeloproliferative Disorders

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