Clinical Trials Browser

Interventional × Bone Marrow Failure Disorders × 1 year × Clear all

NCT06839456 2026-04-15

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Classical hematologyLymphoidOther hematologic neoplasm

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Anemia, Refractory, with Excess of Blasts, Hemoglobinopathies, Immunologic Deficiency Syndromes, Leukemia, Lymphoma, Non-Hodgkin, Metabolism, Inborn Errors

NCT04644016 2026-03-13

Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders

Phase 2 Recruiting

31 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Bone Marrow Failure Disorders, Anemia, Refractory, with Excess of Blasts, Hemoglobinopathies, Lymphoma, Non-Hodgkin, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT04965597 2026-03-09

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Phase 2 Completed

40 enrolled

Classical hematology

Congenital amegakaryocytic thrombocytopenia, Bone Marrow Failure Disorders, Shwachman-Diamond Syndrome, Anemia, Hypochromic, Hemoglobinuria, Paroxysmal, Anemia, Diamond-Blackfan

NCT02958462 2026-02-23

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Phase NA Recruiting

2,000 enrolled

Classical hematologyOther hematologic neoplasm

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Cytopenia, Neoplastic Syndromes, Hereditary, Hematologic Neoplasms

NCT02356653 2026-02-20

ExpMACs

Phase EARLY_PHASE1 Recruiting

100 enrolled

Other hematologic neoplasm

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome, Bone Marrow Failure Disorders, Immunologic Deficiency Syndromes, Leukemia, Metabolism, Inborn Errors

NCT07408583 2026-02-19

Prenatal Transplantation for Fetuses With Fanconi Anemia

Phase 1/2 Not yet recruiting

12 enrolled

Classical hematology

Bone Marrow Failure Disorders, Congenital Bone Marrow Failure Syndromes, Fanconi Anemia, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Anemia, Hypoplastic, Congenital, Genetic Diseases, Inborn, DNA Repair-Deficiency Disorders

NCT03622788 2025-12-17

Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant

Phase 1/2 Active not recruiting

16 enrolled

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

Bone Marrow Failure Disorders, Anemia, Aplastic, Hodgkin Disease, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06430788 2025-12-17

A Study of Emapalumab for Pediatric Aplastic Anemia

Phase 2 Recruiting

35 enrolled

Classical hematology

Bone Marrow Failure Disorders, Cytopenia, Anemia, Aplastic

NCT05236764 2025-10-30

HAPLOTAB

Phase NA Active not recruiting

3 enrolled 9 charts

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

Bone Marrow Failure Disorders, Primary Immunodeficiency Diseases, Cytopenia, Anemia, Aplastic, Hemoglobinopathies, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphohistiocytosis, Hemophagocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT06940570 2025-10-23

MATCH

Phase 3 Suspended

60 enrolled

Classical hematologyOtherOther hematologic neoplasm

Bone Marrow Failure Disorders, Anemia, Aplastic, Leukemia, Neoplasms, Pain, Intractable, Mucositis

NCT02722668 2025-07-04

UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

Phase 2 Completed

15 enrolled 15 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Bone Marrow Failure Disorders, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Leukemia, Plasma Cell, Lymphoma, Follicular, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT02988466 2025-05-28

Reduced Intensity (RIC) Conditioning And Transplantation of HLA-Haplo-HCT

Phase 2 Completed

78 enrolled 16 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Bone Marrow Failure Disorders, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Follicular, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Acute, Lymphoma, T-Cell, Neoplasm, Residual, Lymphoma, B-Cell, Marginal Zone, Hematologic Neoplasms, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis