Clinical Trials

DermatologicGenitourinaryHead & NeckOther solid neoplasmSarcomaThoracic

Bone Neoplasms, Sarcoma, Ewing, Osteosarcoma

NCT03420963 2026-03-20

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Phase 1 Terminated

12 enrolled

Mesothelioma, Malignant, Bone Neoplasms, Endocrine Gland Neoplasms, Melanoma, Mouth Neoplasms, Pharyngeal Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Urologic Neoplasms

NCT03965234 2026-03-17

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Phase 1/2 Recruiting

99 enrolled

GastrointestinalSarcoma

Bone Neoplasms, Sarcoma, Colorectal Neoplasms

NCT05051059 2026-03-16

QOLSarcoma

60 enrolled

Phase NA Active not recruiting

Bone Neoplasms, Sarcoma

NCT02893397 2026-03-05

Supervised Exercise in Improving Physical Fitness Before Surgery in Patients With Resectable Bone Cancer

45 enrolled

Phase NA Active not recruiting

Bone Neoplasms

NCT04307914 2026-03-05

FURTHER

216 enrolled

Phase NA Active not recruiting

Bone Neoplasms, Neoplasm Metastasis, Neoplasms, Pain

NCT05038124 2026-03-05

A Study of Stereotactic Body Radiotherapy (SBRT) and Surgical Stabilization for People With Cancer That Has Spread to the Bone

39 enrolled

Bone Neoplasms, Neoplasm Metastasis

NCT07193550 2026-02-27

A Phase 2 Trial of Zanzalintinib in Advanced/Metastatic Bone Sarcomas (ZAMBONE)

70 enrolled

Bone Neoplasms

NCT04055220 2026-02-17

REGOSTA

168 enrolled

Pathologic Complete Response, Bone Neoplasms, Chondrosarcoma, Hemangiosarcoma, Leiomyosarcoma, Patient Compliance, Sarcoma, Ewing, Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT04698785 2026-02-17

REGOMAIN

36 enrolled

Bone Neoplasms, Osteosarcoma

NCT05726383 2026-02-10

Iscador® P (Mistletoe) Immunotherapy for Recurrent Osteogenic Sarcoma

32 enrolled

Bone Neoplasms, Neoplasm Metastasis, Sarcoma

NCT05746429 2026-02-04

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer

68 enrolled 20 charts

Bone Neoplasms, Neoplasms

NCT05419518 2026-01-23

Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas

124 enrolled

Phase 1 Active not recruiting

Bone Neoplasms, Neoplasm Metastasis

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT07314424 2026-01-02

The Effect of Preoperative Intravenous Ferric Derisomaltose and EPO and Tranexamic Acid in Patients With Preoperative Anemia or Iron Deficiency in Bone Tumor

Phase 4 Not yet recruiting

160 enrolled

Classical hematologySarcoma

Anemia, Bone Neoplasms

NCT06562673 2025-12-29

IACE-OS

Phase 1/2 Completed

10 enrolled

Bone Neoplasms, Osteosarcoma

NCT02811523 2025-11-26

In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma

Phase 1 Recruiting

17 enrolled

Phase 2 Active not recruiting

Bone Neoplasms, Sarcoma

NCT03449108 2025-11-21

LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas

BreastEndocrineGynecologicHead & NeckSarcoma

Bone Neoplasms, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Giant Cell Tumor of Bone, Histiocytoma, Malignant Fibrous, Triple Negative Breast Neoplasms, Thyroid Carcinoma, Anaplastic

NCT05312411 2025-11-20

A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma

Phase 1 Active not recruiting

21 enrolled

DermatologicGenitourinarySarcoma

Bone Neoplasms, Osteosarcoma

NCT03093909 2025-11-10

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Phase 1 Recruiting

44 enrolled

Bone Neoplasms, Melanoma, Osteosarcoma, Urologic Neoplasms

NCT06171945 2025-10-27

AYAConnect

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOtherOther hematologic neoplasmSarcoma

63 enrolled

Psychological Well-Being, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Motor Activity, Mouth Neoplasms, Neoplasms, Obesity, Pancreatic Neoplasms, Pharyngeal Neoplasms, Rectal Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Weight Loss, Endometrial Neoplasms, Overweight

NCT05621668 2025-10-20

A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma

Phase 1 Recruiting

40 enrolled

Phase 4 Enrolling by invitation

Bone Neoplasms, Sarcoma

NCT03244020 2025-10-03

LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology

2,868 enrolled

Classical hematologySarcoma

Bone Neoplasms, Hematoma, Sarcoma, Venous Thromboembolism

NCT04515459 2025-09-15

EPOP-SARCOMA

53 enrolled

Phase 2 Active not recruiting

Bone Neoplasms, Sarcoma

NCT02880319 2025-09-09

Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone

150 enrolled 12 charts

Bone Neoplasms

NCT06582849 2025-08-26

EARN

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

33 enrolled

Anus Neoplasms, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Lymphoma, Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Skin Neoplasms, Stomach Neoplasms, Testicular Neoplasms, Thyroid Neoplasms, Uterine Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Hematologic Neoplasms

NCT07056946 2025-07-15

Supra Inguinal Fascia Iliaca Block Versus Ultrasound-guided Caudal Analgesia for Pediatrics Undergoing Anterior and Lateral Thigh Surgeries: A Randomized Controlled Trial

Phase NA Not yet recruiting

70 enrolled

Bone Neoplasms

NCT00592293 2025-07-03

Proton Radiation for the Treatment of Pediatric Bone and Non-Rhabdomyosarcoma Soft Tissue Sarcomas

70 enrolled 9 charts

Phase 3 Active not recruiting

Bone Neoplasms, Sarcoma

NCT05115331 2025-05-31

1-2 PUNCH

168 enrolled

Phase NA Enrolling by invitation

Bone Diseases, Bone Neoplasms

NCT06743958 2025-05-28

Prehab4Kids

16 enrolled

Bone Neoplasms, Neoplasms, Sarcoma

NCT06129903 2025-05-16

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

60 enrolled

Bone Neoplasms, Sarcoma

NCT06165419 2025-05-14

Definitive Radiation for High-Risk Spine Metastases

Phase EARLY_PHASE1 Active not recruiting

26 enrolled

BreastSarcomaThoracic

Bone Neoplasms, Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis

NCT04634227 2025-05-04

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

Bone Neoplasms, Sarcoma

NCT06881498 2025-04-15

A Substudy of the Effect of Acute Normovolemic Hemodilution in Bone Tumor Surgery

32 enrolled

Bone Neoplasms

NCT06459141 2025-03-14

The Effect of Acute Normovolemic Hemodilution in Bone Tumor Surgery

150 enrolled

Bone Neoplasms

NCT05131815 2025-02-26

The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidOther hematologic neoplasmPlasma cellSarcomaThoracic

8 enrolled

Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Gastrointestinal Neoplasms, Glioblastoma, Head and Neck Neoplasms, Hodgkin Disease, Leukemia, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Motor Activity, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Sarcoma, Skin Neoplasms, Thyroid Neoplasms, Colorectal Neoplasms

NCT03154190 2025-01-24

Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer

BreastDermatologicGastrointestinalGenitourinaryGynecologicMyeloidOther hematologic neoplasmSarcomaThoracic

128 enrolled 24 charts

Urinary Bladder Neoplasms, Bone Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Esophageal Neoplasms, Melanoma, Myelodysplastic Syndromes, Ovarian Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Recurrence, Sarcoma, Stomach Neoplasms, Leukemia, Myeloid, Acute, Disease Progression, Triple Negative Breast Neoplasms

NCT04410042 2024-12-20

Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure

Phase 3 Terminated

15 enrolled 13 charts

Bone Neoplasms

NCT04963517 2024-12-06

proGAIT

Phase 2/3 Completed

11 enrolled

Bone Neoplasms, Motor Activity

NCT04183062 2024-11-08

BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases

Phase 2 Withdrawn

Bone Neoplasms, Sarcoma

NCT06669013 2024-11-01

FollowTheDIN

Phase 3 Recruiting

40 enrolled

Bone Neoplasms, Rhabdomyosarcoma, Alveolar, Rhabdomyosarcoma, Embryonal

NCT03277924 2024-08-13

ImmunoSarc

Phase 1/2 Completed

197 enrolled

Chondrosarcoma, Extraskeletal Myxoid, Bone Neoplasms, Chondrosarcoma, Hemangioendothelioma, Hemangiosarcoma, Leiomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Hemangioendothelioma, Epithelioid, Histiocytoma, Malignant Fibrous, Solitary Fibrous Tumors

NCT01803152 2024-07-03

Dendritic Cell Vaccine for Children and Adults With Sarcoma

Phase 1 Completed

19 enrolled

Bone Neoplasms, Sarcoma

NCT04740749 2024-07-01

Compress

Phase NA Terminated

200 enrolled

Phase EARLY_PHASE1 Unknown

Bone Neoplasms

NCT06455722 2024-06-12

[68Ga]Ga-P15-041 PET/CT in Variety of Bone Tumors

Phase EARLY_PHASE1 Completed

Bone Neoplasms

NCT05075889 2024-05-14

Utility of ICG in Benign Bone Tumors

2 enrolled

Bone Neoplasms

NCT05057130 2024-04-01

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Phase 2/3 Unknown

50 enrolled

Bone Neoplasms, Neoplasms, Connective Tissue, Sarcoma, Osteosarcoma, Neoplasms, Connective and Soft Tissue

NCT05057143 2024-04-01

3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors

Phase NA Unknown

Bone Neoplasms, Osteosarcoma

NCT06302465 2024-03-29

Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells

60 enrolled