Announcements Trials
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Phase

Phase 3 1Phase 2 1

Status

Recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Ovarian Neoplasms 20Breast Neoplasms 11Prostatic Neoplasms 10Neoplasms 7Neoplasm Metastasis 7Fallopian Tube Neoplasms 7Pancreatic Neoplasms 6Endometrial Neoplasms 5Triple Negative Breast Neoplasms 4Lung Neoplasms 3Head and Neck Neoplasms 3Glioblastoma 3Carcinoma, Ovarian Epithelial 3Small Cell Lung Carcinoma 2Prostatic Neoplasms, Castration-Resistant 2Glioma 2Carcinoma, Non-Small-Cell Lung 2Brain Neoplasms 2Biliary Tract Neoplasms 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urologic Neoplasms 1Urinary Bladder Neoplasms 1Unilateral Breast Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Sarcoma 1SCLC,Extensive Stage 1Recurrence 1Rectal Neoplasms 1Prostate Adenocarcinoma 1

Interventions

Radiosurgery 50Magnetic Resonance Spectroscopy 34Temozolomide 28Bevacizumab 24pembrolizumab 23Radiotherapy 20Nivolumab 20Specimen Handling 14Ipilimumab 13Cyclophosphamide 13Mental Status and Dementia Tests 12Carboplatin 12abemaciclib 10Radiation 10trastuzumab deruxtecan 8Proton Therapy 7Pemetrexed 7Memantine 7Blood Specimen Collection 7fluciclovine F-18 6binimetinib 6Paclitaxel 6Lomustine 6Etoposide 6Cisplatin 6Capecitabine 6encorafenib 5Trastuzumab 5Surveys and Questionnaires 5Surgical Procedures, Operative 5

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Brain Neoplasms × niraparib × 1 year × Clear all
NCT06388733 2026-04-01

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NeuroTrials, LLC

Phase 3 Recruiting
450 enrolled
CNS

Brain Neoplasms, Glioblastoma

NCT05700721 2026-02-05

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

M.D. Anderson Cancer Center

Phase 2 Recruiting
120 enrolled
CNS

Brain Neoplasms

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