Clinical Trials
515 trialsSTARTRK-2
Hoffmann-La Roche
IMPACT
University of Florida
Radcav
University Hospital Heidelberg
ADAGiO
University of Florida
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Duke Street Bio Ltd
Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors
University of Michigan Rogel Cancer Center
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII
Black Diamond Therapeutics, Inc.
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
National Institutes of Health Clinical Center (CC)
A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
Exelixis
Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer
National Cancer Institute (NCI)
A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors
Hoffmann-La Roche
ACTION-Brain
University of Vermont Medical Center
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
National Institutes of Health Clinical Center (CC)
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery
Thomas Jefferson University
A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy
Eli Lilly and Company
A Study of Sotorasib in People With Brain Tumors
Memorial Sloan Kettering Cancer Center
Peds IMPACT
University of Florida
Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors
National Institutes of Health Clinical Center (CC)
Measuring Brain Changes Following Cognitive Intervention in Pediatric Patients With Brain Tumors
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer
M.D. Anderson Cancer Center
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
M.D. Anderson Cancer Center
Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
NRG Oncology
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
Pfizer
FACILITATE
Baptist Health South Florida
NEURO-SUTURE
Medical University of Warsaw
Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases
NRG Oncology
PIRe
Rigshospitalet, Denmark
Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.
Universitaire Ziekenhuizen KU Leuven
Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases
Stanford University
HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors
M.D. Anderson Cancer Center
RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)
University of Florida
Radiosurgery Before Surgery for the Treatment of Brain Metastases
Emory University
Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma
National Cancer Institute (NCI)
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
National Institutes of Health Clinical Center (CC)
Brodalumab in the Treatment of Immune-Related Adverse Events
Columbia University
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Canadian Cancer Trials Group
DESTINY-B12
AstraZeneca
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
Roswell Park Cancer Institute
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors
Medical College of Wisconsin
MeDex: No Perioperative Dexamethasone in Brain Metastases
University of Louisville
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Vanderbilt-Ingram Cancer Center
Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study
Case Comprehensive Cancer Center
Stereotactic Radiosurgery Dose Escalation for Brain Metastases
University of Utah
TUXEDO-4
MedSIR
A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 Gliomas
Case Comprehensive Cancer Center
Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas
National Cancer Institute (NCI)
Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis
Emory University
MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases
Duke University
Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases
SWOG Cancer Research Network
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
University of Maryland, Baltimore