Announcements Trials
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Phase

Phase 3 2Phase NA 1Phase 1 1

Status

Active not recruiting 2Terminated 1Completed 1

Sponsor Class

OTHER 2NIH 1INDUSTRY 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Thoracic 2Breast 2Genitourinary 1Gastrointestinal 1Dermatologic 1

Conditions

Multiple Myeloma 35Prostatic Neoplasms 31Carcinoma, Non-Small-Cell Lung 30Breast Neoplasms 27Lymphoma 20Lymphoma, Non-Hodgkin 18Hematologic Neoplasms 14Squamous Cell Carcinoma of Head and Neck 12Leukemia, Lymphocytic, Chronic, B-Cell 12Hodgkin Disease 12Sarcoma 11Neoplasm Metastasis 11Pancreatic Neoplasms 10Neoplasms 10Lung Neoplasms 10Leukemia, Myeloid, Acute 10Head and Neck Neoplasms 10Colorectal Neoplasms 10Carcinoma, Renal Cell 10Triple Negative Breast Neoplasms 9Ovarian Neoplasms 9Melanoma 9Lymphoma, Large B-Cell, Diffuse 9Glioma 8Wilms Tumor 7Urinary Bladder Neoplasms 7Stomach Neoplasms 7Sarcoma, Ewing 7Rhabdomyosarcoma 7Rhabdoid Tumor 7

Interventions

trastuzumab deruxtecan 1sapanisertib 1Specimen Handling 1Radiosurgery 1Memantine 1Magnetic Resonance Spectroscopy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Has results × Brain Neoplasms × 30 days × Clear all
NCT04250545 2026-05-26

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 1 Active not recruiting
22 enrolled 14 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Neoplasms

NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

NRG Oncology

Phase 3 Terminated
19 enrolled 19 charts
BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

NCT04739761 2026-05-12

DESTINY-B12

AstraZeneca

Phase 3 Active not recruiting
506 enrolled 27 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01705548 2026-05-07

Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis

Emory University

Phase NA Completed
24 enrolled 16 charts
CNS

Brain Neoplasms

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