Announcements Trials
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Phase

Phase 3 1Phase 2 1Phase 1 1

Status

Terminated 1Recruiting 1Active not recruiting 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Thoracic 2Genitourinary 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Lung Neoplasms 22Leukemia, Myeloid, Acute 22Breast Neoplasms 20Neoplasm Metastasis 17Pancreatic Neoplasms 15Multiple Myeloma 14Prostatic Neoplasms 13Melanoma 13Colorectal Neoplasms 12Carcinoma, Non-Small-Cell Lung 12Lymphoma 11Carcinoma, Renal Cell 11Burkitt Lymphoma 10Triple Negative Breast Neoplasms 9Urinary Bladder Neoplasms 8Squamous Cell Carcinoma of Head and Neck 8Ovarian Neoplasms 8Myelodysplastic Syndromes 8Mouth Neoplasms 8Glioma 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Oropharyngeal Neoplasms 7Leukemia, Lymphocytic, Chronic, B-Cell 7Laryngeal Neoplasms 7Fallopian Tube Neoplasms 7Carcinoma, Hepatocellular 7Carcinoma 7Sarcoma 6Nasopharyngeal Carcinoma 6Endometrial Neoplasms 6

Interventions

Radiosurgery 7Temozolomide 6pembrolizumab 4Magnetic Resonance Spectroscopy 4Bevacizumab 4Specimen Handling 3Nivolumab 3abemaciclib 2Watchful Waiting 2Surveys and Questionnaires 2Receptors, Interleukin-8B 2Radiation 2Mental Status and Dementia Tests 2Memantine 2Ipilimumab 2Biopsy 2vorasidenib 1sotorasib 1sapanisertib 1ribociclib 1pertuzumab 1osimertinib 1lenvatinib 1fluciclovine F-18 1entrectinib 1encorafenib 1elacestrant 1dexamethasone acetate 1dexamethasone 21-phosphate 1brivaracetam 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Brain Neoplasms × Specimen Handling × 30 days × Clear all
NCT02971501 2026-05-29

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

National Cancer Institute (NCI)

Phase 2 Active not recruiting
5 enrolled 9 charts
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06914479 2026-05-27

Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors

University of Michigan Rogel Cancer Center

Phase 1 Recruiting
11 enrolled
CNS

Brain Neoplasms

NCT04588246 2026-05-20

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

NRG Oncology

Phase 3 Terminated
19 enrolled 19 charts
BreastCNSDermatologicGastrointestinalGenitourinaryThoracic

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Gastrointestinal Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Small Cell Lung Carcinoma

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