Clinical Trials

Brain Neoplasms

NCT04711824 2025-12-23

SOLARA

Phase 1/2 Recruiting

41 enrolled

Brain Neoplasms, Breast Neoplasms

NCT04965064 2025-12-15

Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

Phase 2 Recruiting

22 enrolled

Brain Neoplasms, Breast Neoplasms

NCT06764940 2025-11-28

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

Phase 2 Recruiting

120 enrolled

Brain Neoplasms, Breast Neoplasms

NCT05535413 2025-04-25

UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases

Phase 1/2 Recruiting

30 enrolled

Brain Neoplasms

NCT03213002 2025-04-09

CAPTEM

Phase 1/2 Recruiting

67 enrolled

Phase 2 Not yet recruiting

Brain Neoplasms, Glioblastoma, Neoplasms

NCT06374888 2024-04-19

Nilatinib Maleate Tablets Combined With Capecitabine in the Treatment of HER2-positive Advanced Esophageal/Esophagogastric Junction/Gastric Adenocarcinoma With Brain Metastases

28 enrolled

Brain Neoplasms

NCT02614794 2023-08-14

HER2CLIMB

612 enrolled 30 charts 1 FDA

Brain Neoplasms, Breast Neoplasms

NCT03613181 2023-04-24

ANGLeD

Phase 3 Unknown

150 enrolled

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT02000882 2022-02-07

STAR Cape+BKM120 MBC With Brain Met

10 enrolled 11 charts

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00820222 2019-04-02

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer

Phase 3 Completed

540 enrolled 18 charts

Brain Neoplasms, Breast Neoplasms

NCT01132664 2016-08-17

Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer

Phase 1/2 Terminated

72 enrolled 15 charts

Brain Neoplasms, Breast Neoplasms

NCT00437073 2015-10-15

Brain Metastases In ErbB2-Positive Breast Cancer

Phase 2 Terminated

22 enrolled 8 charts

Brain Neoplasms, Breast Neoplasms

NCT00570908 2014-09-18

Brain Mets - Capecitabine Plus Sunitinib and WBRT

Phase 2 Terminated

12 enrolled 7 charts

Brain Neoplasms, Breast Neoplasms

NCT00795678 2013-08-02

Chemotherapeutic Agents in Brain/Breast

Completed

10 enrolled

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

NCT00967031 2013-01-18

Lapatinib Ditosylate and Capecitabine in Treating Patients With Stage IV Breast Cancer and Brain Metastases

45 enrolled

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00227656 2012-12-11

Capecitabine and Pegylated Interferon Alfa-2a in Treating Patients With Recurrent or Progressive Brain Metastases Due to Breast Cancer

Phase 2 Terminated

2 enrolled

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Breast Neoplasms, Male

NCT00504660 2012-01-11

6-TG, Capecitabine and Celecoxib Plus TMZ or CCNU for Anaplastic Glioma Patients

75 enrolled 8 charts