Announcements Trials
Browse Landscape

Phase

Phase 1 2

Status

Completed 16Active not recruiting 6Recruiting 5Terminated 4Not yet recruiting 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Breast Neoplasms 12Lymphoma, Large B-Cell, Diffuse 10Triple Negative Breast Neoplasms 8Recurrence 6Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, B-Cell 6Neoplasm Metastasis 4Multiple Myeloma 4Leukemia, Myeloid, Acute 4Leukemia 4Neuroblastoma 3Lymphoma, Non-Hodgkin 3Lymphoma, Mantle-Cell 3Lymphoma, B-Cell, Marginal Zone 3Lymphoma 3Hematologic Neoplasms 3Head and Neck Neoplasms 3Graft vs Host Disease 3Squamous Cell Carcinoma of Head and Neck 2Oropharyngeal Neoplasms 2Neoplasms, Plasma Cell 2Lymphoma, Follicular 2Hodgkin Disease 2Dendritic Cell Sarcoma, Interdigitating 2Carcinoma, Renal Cell 2Brain Neoplasms 2Wilms Tumor 1Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Cervical Neoplasms 1

Interventions

aflutinib 3Saline Solution 3Radiotherapy 3Temozolomide 2Receptors, Interleukin-8B 2Radiosurgery 2Pemetrexed 2Memantine 2Indocyanine Green 2Dexmedetomidine 2Cyclophosphamide 2Carboplatin 2Blood Specimen Collection 2Bevacizumab 2Aminolevulinic Acid 2urinastatin 1trastuzumab deruxtecan 1tovorafenib 1sacituzumab govitecan 1posaconazole 1pembrolizumab 1peginterferon alfa-2b 1osimertinib 1neratinib 1montelukast 1gallium maltolate 1fludarabine 1dalpiciclib 1asciminib 1anlotinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Not yet recruiting × Brain Neoplasms × Cyclophosphamide × Clear all
NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Dana-Farber Cancer Institute

Phase 1 Not yet recruiting
70 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT07199413 2025-09-30

Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases

Medical College of Wisconsin

Phase 1 Not yet recruiting
20 enrolled
CNS

Brain Neoplasms, Meningeal Carcinomatosis

Data powered by HemOnc (CC BY 4.0) Colophon âš¡