Announcements Trials
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Phase

Phase 1 3Phase 3 1Phase 1/2 1

Status

Completed 5Terminated 1

Sponsor Class

INDUSTRY 3NIH 2

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Sarcoma 2

Conditions

Glioma 8Glioblastoma 8Astrocytoma 7Brain Neoplasms 5Central Nervous System Neoplasms 3Recurrence 2Gliosarcoma 2Oligodendroglioma 1Neoplasms 1

Interventions

Temozolomide 94Radiotherapy 59Bevacizumab 59Radiosurgery 41Carboplatin 27Irinotecan 26Magnetic Resonance Spectroscopy 25Surgical Procedures, Operative 23Etoposide 22Carmustine 20Filgrastim 18Erlotinib Hydrochloride 17Cyclophosphamide 16Cisplatin 16Vincristine 15Lomustine 15Lapatinib 15Sorafenib 13Radiation 13Trastuzumab 12Nivolumab 12Imatinib Mesylate 12Thalidomide 11Surveys and Questionnaires 11Granulocyte Colony-Stimulating Factor 11Radiotherapy, Intensity-Modulated 10Aminolevulinic Acid 10temsirolimus 9Topotecan 9Thiotepa 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Brain Neoplasms × IL13-PE38 × Clear all
NCT00036972 2013-06-26

Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00006268 2013-06-24

Immunotoxin Therapy in Treating Patients With Malignant Glioma

National Cancer Institute (NCI)

Phase 1/2 Completed
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00089427 2011-07-04

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

INSYS Therapeutics Inc

Phase 1 Completed
24 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00064779 2011-06-06

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

INSYS Therapeutics Inc

Phase 1 Completed
18 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT00076986 2011-06-06

The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme

INSYS Therapeutics Inc

Phase 3 Completed
300 enrolled
CNS

Brain Neoplasms, Glioblastoma, Glioma

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