Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase EARLY_PHASE1 1Phase 3 1

Status

Unknown 5Completed 5Terminated 4Not yet recruiting 2Active not recruiting 2

Sponsor Class

OTHER 5

Study Type

Interventional 5

Sponsor

Cancer Type

CNS 5Thoracic 1Sarcoma 1Lymphoid 1

Conditions

Carcinoma, Non-Small-Cell Lung 72Lung Neoplasms 9Adenocarcinoma of Lung 7Brain Neoplasms 5Non-squamous Non-small Cell Lung Cancer 4NSCLC 4Adenocarcinoma 4Mesothelioma, Malignant 3Colorectal Neoplasms 3Nonsquamous Non-Small Cell Lung Cancer 2Non-squamous Cell Non-Small Cell Lung Cancer 2Neoplasms 2Meningeal Carcinomatosis 2Lymphoma 2Glioma 2Central Nervous System Neoplasms 2Urinary Bladder Neoplasms 1Ureteral Neoplasms 1Untreated Advanced Non-Small Cell Lung Cancer 1Unresectable Stage III NSCLC 1Thyroid Neoplasms 1Thyroid Carcinoma, Anaplastic 1Thoracic Neoplasms 1Stomach Neoplasms 1Stereotactic Radiotherapy; Evoximab (AK112); New Adjuvant Therapy for Non-small Cell Lung Cancer 1Staging IV NSCLC 1Squamous Cell Lung Cancer 1Squamous Cell Carcinoma of Head and Neck 1Solid Tumor 1Respiratory Tract Neoplasms 1

Interventions

Radiosurgery 12Temozolomide 10Radiotherapy 10Magnetic Resonance Spectroscopy 7Erlotinib Hydrochloride 6Bevacizumab 6Surgical Procedures, Operative 5Pemetrexed 5Gefitinib 5Drug Therapy 5Carboplatin 5pyrotinib 4icotinib 4aumolertinib 4Trastuzumab 3Spermine Synthase 3Radiation 3Lomustine 3Etoposide 3Dexmedetomidine 3Chlorotoxin 3Carmustine 3osimertinib 2camrelizumab 2apatinib 2Tyrosine Kinase Inhibitors 2Thiotepa 2Surveys and Questionnaires 2Sevoflurane 2Propofol 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Unknown × Brain Neoplasms × Pemetrexed × Clear all
NCT04211090 2022-11-16

CAP-BRAIN

Sun Yat-sen University

Phase 2 Unknown
45 enrolled
CNS

Brain Neoplasms

NCT05459441 2022-07-15

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

Shanghai Pudong Hospital

Phase EARLY_PHASE1 Unknown
30 enrolled
CNS

Brain Neoplasms, Glioma

NCT01951469 2022-03-08

Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer

Sun Yat-sen University

Phase 3 Unknown
160 enrolled
CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00276783 2020-03-05

Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Metastases

Northwestern University

Phase 2 Unknown
31 enrolled
CNSLymphoidSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Lymphoma, Neoplasm Metastasis, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT02284490 2014-11-06

High-dose Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases

Shandong Cancer Hospital and Institute

Phase 2 Unknown
25 enrolled
CNS

Brain Neoplasms

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