NCT03550391 2026-04-14
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Canadian Cancer Trials Group
Phase 3 Recruiting
Clinical Trials
23 trialsNCT04804644 2026-04-03
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
NRG Oncology
Phase 3 Recruiting
NCT05438212 2026-04-03
Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases
NRG Oncology
Phase 3 Active not recruiting
NCT06500455 2026-04-03
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
NRG Oncology
Phase 3 Recruiting
NCT01592968 2026-03-09
Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases
M.D. Anderson Cancer Center
Phase 3 Active not recruiting
NCT00950001 2026-02-20
Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases
M.D. Anderson Cancer Center
Phase 3 Active not recruiting
NCT04114981 2026-01-26
Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
Alliance for Clinical Trials in Oncology
Phase 3 Active not recruiting
NCT03750227 2025-12-24
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Mayo Clinic
Phase 3 Recruiting
NCT04365374 2025-10-07
Post-Surgical Stereotactic Radiotherapy (SRT) Versus GammaTile-ROADS (Radiation One and Done Study)
GT Medical Technologies, Inc.
Phase 3 Active not recruiting
NCT03741673 2025-09-05
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases
M.D. Anderson Cancer Center
Phase 3 Recruiting
NCT04474925 2025-07-18
Pre- Versus Post-operative SRS for Resectable Brain Metastases
AHS Cancer Control Alberta
Phase 3 Terminated
NCT04588246 2025-06-06
Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
NRG Oncology
Phase 3 Terminated
NCT05144867 2023-10-17
SRSvsWBRT
Post Graduate Institute of Medical Education and Research, Chandigarh
Phase 3 Unknown
NCT00377156 2022-09-16
Stereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Alliance for Clinical Trials in Oncology
Phase 3 Completed
NCT01372774 2022-09-16
Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery
Alliance for Clinical Trials in Oncology
Phase 3 Completed
NCT00096265 2018-03-09
Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer
National Cancer Institute (NCI)
Phase 3 Terminated
NCT01169129 2014-02-04
Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases
Barretos Cancer Hospital
Phase 3 Withdrawn
NCT00002708 2013-11-19
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
Radiation Therapy Oncology Group
Phase 3 Completed
NCT00002899 2012-07-02
Adjuvant Radiation Therapy in Treating Patients With Brain Metastases
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3 Terminated
NCT00460395 2012-02-24
Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial
M.D. Anderson Cancer Center
Phase 3 Completed
NCT01535209 2012-02-17
Stereotactic Radiotherapy of Resection Cavity For Single Brain Metastasis Versus Whole-Brain Radiotherapy After Resection
Maria Sklodowska-Curie National Research Institute of Oncology
Phase 3 Unknown
NCT01353573 2011-05-13
TRICK
Hamilton Health Sciences Corporation
Phase 3 Unknown
NCT00124761 2010-09-06
A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases
Royal Adelaide Hospital
Phase 3 Completed