Clinical Trials Browser

Phase 2 × Brain Neoplasms × Radiotherapy × Clear all

NCT02792582 2026-04-23

A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection

Phase 2 Active not recruiting

Brain Neoplasms, Craniopharyngioma

NCT05013892 2026-04-16

NTS-WBRT in Brain Metastases

Phase 2 Recruiting

Brain Neoplasms

NCT05535166 2026-02-12

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Phase 2 Recruiting

Brain Neoplasms, Medulloblastoma

NCT06991101 2025-12-26

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Phase 2 Recruiting

Brain Neoplasms, Glioblastoma

NCT01878617 2025-11-13

A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma

Phase 2 Active not recruiting

Brain Neoplasms, Medulloblastoma, Infratentorial Neoplasms, Neuroectodermal Tumors, Primitive

NCT06462079 2024-06-17

Sacituzumab Govitecan Combined With Head Radiotherapy for Her2-negative Breast Cancer Brain Metastases

Phase 2 Not yet recruiting

Brain Neoplasms, Breast Neoplasms

NCT01854554 2024-01-02

Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT)

Phase 2 Completed

90 enrolled 11 charts

Brain Neoplasms, Glioblastoma

NCT00895622 2023-09-08

Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

Phase 2 Completed

244 enrolled 15 charts

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT00080938 2023-06-29

Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer

Phase 2 Completed

26 enrolled 8 charts

Adenocarcinoma of Lung, Brain Neoplasms, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00187226 2023-05-31

A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects

Phase 2 Completed

361 enrolled 11 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT01730950 2022-12-29

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Phase 2 Completed

182 enrolled 19 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00871923 2021-09-16

Tarceva With Whole Brain Radiation Therapy - Brain Mets From Non-Small Cell Lung Cancer

Phase 2 Completed

44 enrolled 16 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00049361 2021-09-09

Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases

Phase 2 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Phase 2 Completed

38 enrolled 53 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT01414738 2021-01-26

Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases

Phase 2 Completed

50 enrolled 20 charts

Brain Neoplasms

NCT01740258 2021-01-26

BBP

Phase 2 Completed

68 enrolled 11 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00031967 2020-10-22

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Phase 2 Completed

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries

NCT01567202 2020-09-09

Study of DC Vaccination Against Glioblastoma

Phase 2 Unknown

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00027846 2019-08-07

Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma

Phase 2 Completed

378 enrolled 16 charts

Brain Neoplasms, Central Nervous System Neoplasms

NCT00238264 2019-08-07

Radiation Therapy in Treating Young Patients With Gliomas

Phase 2 Completed

92 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT01868906 2018-08-24

FMISOPETSCS

Phase 2 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00047320 2018-02-14

Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors

Phase 2 Completed

104 enrolled 12 charts

Brain Neoplasms, Teratoma, Central Nervous System Neoplasms

NCT00782756 2018-02-06

Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma

Phase 2 Completed

40 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT03356600 2017-12-11

Apatinib Plus Radiotherapy for Patients With Brain Metastases From Non-small-cell Lung Cancer

Phase 2 Unknown

Brain Neoplasms

NCT01508117 2017-09-19

Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) Patients

Phase 2 Terminated

1 enrolled 9 charts

Brain Neoplasms, Glioblastoma

NCT00280748 2017-06-23

NRR

Phase 2 Terminated

10 enrolled 14 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00068666 2016-12-15

Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System

Phase 2 Terminated

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00302159 2016-08-18

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

Phase 2 Completed

43 enrolled 14 charts

Brain Neoplasms, Glioblastoma

NCT01213407 2016-05-19

GBM-Vax

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT02104193 2016-02-17

Simvastatin Effect on Radiation Therapy of Brain Metastases

Phase 2 Completed

Brain Neoplasms

NCT02599090 2015-11-06

Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma

Phase 2 Withdrawn

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00003573 2014-07-25

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

Phase 2 Completed

Brain Neoplasms, Central Nervous System Neoplasms

NCT00597402 2014-05-07

Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas

Phase 2 Completed

125 enrolled 9 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00003203 2013-08-23

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

Phase 2 Completed

Brain Neoplasms, Neuroblastoma, Central Nervous System Neoplasms

NCT00637637 2013-08-12

External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases

Phase 2 Unknown

BreastCNSDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOther hematologic neoplasmSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Thyroid Cancer, Papillary, Anus Neoplasms, Urinary Bladder Neoplasms, Brain Neoplasms, Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Colonic Neoplasms, Esophageal Neoplasms, Hodgkin Disease, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mouth Neoplasms, Mycosis Fungoides, Nasopharyngeal Neoplasms, Neoplasms, Wilms Tumor, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Parathyroid Neoplasms, Penile Neoplasms, Pheochromocytoma, Prostatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Sezary Syndrome, Stomach Neoplasms, Tongue Neoplasms, Vaginal Neoplasms, Vulvar Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Esthesioneuroblastoma, Olfactory, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Histiocytoma, Malignant Fibrous, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00002608 2013-07-10

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Phase 2 Completed

CNSEndocrineGastrointestinalHead & NeckOther solid neoplasmSarcomaThoracic

Familial ependymoma, Thyroid Cancer, Papillary, Mesothelioma, Malignant, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Medulloblastoma, Oligodendroglioma, Pheochromocytoma, Sarcoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Adenocarcinoma, Follicular, Adrenocortical Carcinoma, Carcinoma, Medullary, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma, Thyroid Carcinoma, Anaplastic

NCT00004024 2013-04-05

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Phase 2 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

NCT00238251 2012-06-05

Radiation Therapy Combined With Either Gefitinib or Temozolomide in Pats With NSCLC and Brain Metastases

Phase 2 Completed

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT01285414 2012-04-11

Verubulin, Radiation Therapy, and Temozolomide to Treat Patients With Newly Diagnosed Glioblastoma Multiforme

Phase 2 Completed

Brain Neoplasms, Glioblastoma

NCT00875355 2009-08-26

Radiation Therapy With or Without Temozolomide in Treating Women With Brain Metastases and Breast Cancer

Phase 2 Unknown

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis