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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Multiple Myeloma 7Prostatic Neoplasms 3Myasthenia Gravis 3Lymphoma 3Plasmacytoma 2Paraproteinemias 2Neoplasms 2Neoplasm Metastasis 2Lymphoma, Non-Hodgkin 2Lymphoma, Mantle-Cell 2Leukemia, Plasma Cell 2Hemangioma 2Breast Neoplasms 2Anatomic Stage IV Breast Cancer AJCC v8 2Spinal Cord Compression 1Recurrence 1Radiation Injuries 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Neoplasms, Germ Cell and Embryonal 1Nasopharyngeal Carcinoma 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, B-Cell, Marginal Zone 1Leukemia, Lymphocytic, Chronic, B-Cell 1Hepatitis 1Head and Neck Neoplasms 1Glioma 1Gallstones 1Esophageal Stenosis 1

Interventions

Temozolomide 163Radiosurgery 129Radiotherapy 107Bevacizumab 98Magnetic Resonance Spectroscopy 75Carboplatin 48Surgical Procedures, Operative 35pembrolizumab 34Radiation 34Etoposide 34Nivolumab 33Irinotecan 33Cyclophosphamide 33Erlotinib Hydrochloride 31Carmustine 28Lomustine 26Trastuzumab 25Cisplatin 25Ipilimumab 24Filgrastim 23Mental Status and Dementia Tests 21Magnetic Resonance Imaging 21Aminolevulinic Acid 21Vincristine 20Surveys and Questionnaires 19Capecitabine 19Topotecan 18Specimen Handling 18Pemetrexed 18Radiotherapy, Intensity-Modulated 16

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Brain Neoplasms × Steroids × Clear all
NCT00272350 2019-12-05

ZD6474 to Treat Advanced Brain Cancer in Patients

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
83 enrolled
CNS

Brain Neoplasms, Glioma, Neoplasms, Disease Progression

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