Clinical Trials Browser

Terminated × Brain Neoplasms × Temozolomide × Clear all

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

Phase 1/2 Terminated

53 enrolled 22 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT04525014 2024-10-31

PIRATE

Phase 1 Terminated

Brain Neoplasms, Neoplasms, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT03705351 2024-03-04

Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM

Phase 1 Terminated

7 enrolled 12 charts

Brain Neoplasms, Glioblastoma

NCT03190967 2023-10-11

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Phase 1/2 Terminated

12 enrolled 16 charts

Brain Neoplasms, Breast Neoplasms

NCT02343549 2022-11-03

A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)

Phase 2 Terminated

13 enrolled 23 charts

Brain Neoplasms, Neurologic Manifestations

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

Phase 1/2 Terminated

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02046187 2021-06-16

Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma

Phase 1/2 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT01014767 2019-08-20

Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors

Phase 3 Terminated

27 enrolled 1 chart

Brain Neoplasms, Choroid Plexus Neoplasms

NCT01044966 2019-02-12

A Study of Intraventricular Liposomal Encapsulated Ara-C (DepoCyt) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

12 enrolled 12 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00734526 2018-11-09

Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma

Phase 1 Terminated

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT01868906 2018-08-24

FMISOPETSCS

Phase 2 Terminated

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00096265 2018-03-09

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Phase 3 Terminated

126 enrolled 14 charts

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT00638963 2017-06-14

STOP

Phase 2 Terminated

6 enrolled 9 charts

Brain Neoplasms, Breast Neoplasms, Neoplasms, Second Primary

NCT02039778 2017-06-05

STRONG

Phase NA Terminated

4 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT00034697 2017-05-23

Study of Temozolomide in the Treatment of Brain Metastasis From Non-small-cell Lung Cancer (Study P02143)

Phase 2 Terminated

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT00436436 2017-03-28

O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to Previous Temozolomide and Radiation Therapy

Phase 2 Terminated

12 enrolled 10 charts

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00437957 2017-02-23

Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases

Phase 1 Terminated

Brain Neoplasms

NCT00068666 2016-12-15

Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer of the Central Nervous System

Phase 2 Terminated

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT01105702 2016-08-04

Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma

Phase 2 Terminated

28 enrolled 9 charts

Brain Neoplasms, Glioma

NCT00761280 2014-11-14

SAPPHIRE

Phase 3 Terminated

27 enrolled 28 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00005812 2013-05-14

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

Phase 2 Terminated

Brain Neoplasms, Central Nervous System Neoplasms, Meningeal Carcinomatosis

NCT00512798 2012-10-02

Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma

Phase 1/2 Terminated

47 enrolled 9 charts

CNSDermatologic

Brain Neoplasms, Melanoma, Central Nervous System Neoplasms

NCT00717275 2012-10-01

Study of Temozolomide to Treat Newly Diagnosed Brain Metastases

Phase 2 Terminated

3 enrolled 3 charts

Brain Neoplasms

NCT00020839 2012-09-24

Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain

Phase 3 Terminated

CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT00003567 2010-06-11

Gene Therapy and Chemotherapy in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Phase 1 Terminated

CNSLymphoidOther hematologic neoplasmSarcoma

Astrocytoma, Brain Neoplasms, Burkitt Lymphoma, Ependymoma, Glioblastoma, Glioma, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Oligodendroglioma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00376103 2009-09-18

Radiation Boost for Newly Diagnosed Glioblastoma Multiforme

Phase 1/2 Terminated

Brain Neoplasms, Glioblastoma

NCT00548938 2009-09-18

Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM

Phase 2 Terminated

Brain Neoplasms, Glioblastoma, Glioma

NCT00365222 2009-01-22

Phase II Study of Temozolomide in Newly Diagnosed Glioblastoma

Phase 2 Terminated

Brain Neoplasms, Glioblastoma, Neurologic Manifestations, Gliosarcoma