Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 1 1

Status

Completed 4Terminated 2Withdrawn 1Unknown 1

Sponsor Class

OTHER 3NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Sarcoma 1

Conditions

Leukemia, Myeloid, Acute 7Myelodysplastic Syndromes 5Brain Neoplasms 4Lymphoma 3Leukemia 3Glioblastoma 3Sarcoma 2Ovarian Neoplasms 2Lymphoma, Large B-Cell, Diffuse 2Leukemia, Lymphocytic, Chronic, B-Cell 2Glioma 2Astrocytoma 2Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Thyroid Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Spinal Cord Neoplasms 1Solid Tumors 1Small Cell Lung Carcinoma 1Sarcoma, Kaposi 1Refractory Solid Tumors 1Oropharyngeal Neoplasms 1Optic Nerve Glioma 1Neurologic Manifestations 1Neuroectodermal Tumors 1Neoplasms, Neuroepithelial 1Neoplasms 1Mouth Neoplasms 1Mesothelioma, Malignant 1Mesothelioma 1

Interventions

Temozolomide 94Radiotherapy 59Bevacizumab 59Radiosurgery 41Carboplatin 27Irinotecan 26Magnetic Resonance Spectroscopy 25Surgical Procedures, Operative 23Etoposide 22Carmustine 20Filgrastim 18Erlotinib Hydrochloride 17Cyclophosphamide 16Cisplatin 16Vincristine 15Lomustine 15Lapatinib 15Sorafenib 13Radiation 13Trastuzumab 12Nivolumab 12Imatinib Mesylate 12Thalidomide 11Surveys and Questionnaires 11Granulocyte Colony-Stimulating Factor 11Radiotherapy, Intensity-Modulated 10Aminolevulinic Acid 10temsirolimus 9Topotecan 9Thiotepa 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Brain Neoplasms × Valproic Acid × Clear all
NCT01817751 2024-07-17

Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma

Virginia Commonwealth University

Phase 2 Completed
47 enrolled 13 charts
CNS

Brain Neoplasms, Glioblastoma, Glioma, Neurologic Manifestations

NCT00879437 2021-07-21

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

Baylor College of Medicine

Phase 2 Completed
38 enrolled 53 charts
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neuroepithelial, Gliosarcoma

NCT00302159 2016-08-18

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
43 enrolled 14 charts
CNS

Brain Neoplasms, Glioblastoma

NCT00513162 2012-09-19

Valproate and Etoposide for Patients With Neuronal Tumors and Brain Metastases

M.D. Anderson Cancer Center

Phase 1 Completed
8 enrolled
CNS

Brain Neoplasms, Neuroectodermal Tumors

Data powered by HemOnc (CC BY 4.0) Colophon âš¡