Announcements Trials
Browse Landscape

Phase

Phase 2 7Phase 1/2 1Phase 1 1

Status

Recruiting 3Active not recruiting 2Terminated 1Completed 1

Sponsor Class

OTHER 5NETWORK 1INDUSTRY 1

Study Type

Interventional 7

Sponsor

Cancer Type

Dermatologic 7CNS 7

Conditions

Melanoma 21Brain Neoplasms 7Neoplasms 5Colorectal Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Pancreatic Neoplasms 4Lung Neoplasms 4Ovarian Neoplasms 3Neoplasm Metastasis 3Multiple Myeloma 3Hematologic Neoplasms 3Thyroid Neoplasms 2Lymphoma 2Leukemia, Hairy Cell 2Glioma 2Endometrial Neoplasms 2Colonic Neoplasms 2Breast Neoplasms 2Uveal Melanoma 1Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urinary Bladder Neoplasms 1Triple Negative Breast Neoplasms 1Stomach Neoplasms 1Solid Tumor 1Skin Neoplasms 1Recurrence 1Rectal Neoplasms 1Prostatic Neoplasms 1Peripheral Nervous System Neoplasms 1

Interventions

Temozolomide 73Bevacizumab 57Radiotherapy 40Radiosurgery 28Carboplatin 23Nivolumab 17Etoposide 17Cisplatin 17pembrolizumab 16Irinotecan 16Ipilimumab 15Magnetic Resonance Spectroscopy 14Erlotinib Hydrochloride 14Cyclophosphamide 14Carmustine 14Pemetrexed 13Topotecan 10Surgical Procedures, Operative 10Capecitabine 10Lapatinib 9Filgrastim 9Trastuzumab 8Thalidomide 8Sunitinib 8Paclitaxel 8Lomustine 8Aminolevulinic Acid 8encorafenib 7binimetinib 7Vincristine 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

7 trials
RecentStart dateEnrollment
Phase 2 × Brain Neoplasms × binimetinib × Clear all
NCT04074096 2026-03-25

BEPCOME-MB

UNICANCER

Phase 2 Active not recruiting
10 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT02910700 2025-12-17

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

M.D. Anderson Cancer Center

Phase 2 Active not recruiting
52 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT06887088 2025-10-01

ENCEFALO

Grupo Español Multidisciplinar de Melanoma

Phase 2 Recruiting
33 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT04511013 2025-09-11

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

SWOG Cancer Research Network

Phase 2 Recruiting
112 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT03898908 2025-05-21

EBRAIN-MEL

Grupo Español Multidisciplinar de Melanoma

Phase 2 Completed
48 enrolled 24 charts
CNSDermatologic

Brain Neoplasms, Melanoma, Neoplasm Metastasis

NCT03563729 2023-07-13

MEMBRAINS

Herlev Hospital

Phase 2 Recruiting
80 enrolled
CNSDermatologic

Brain Neoplasms, Melanoma

NCT03911869 2023-05-31

POLARIS

Pfizer

Phase 2 Terminated
13 enrolled 55 charts
CNSDermatologic

Brain Neoplasms, Melanoma

Data powered by HemOnc (CC BY 4.0) Colophon âš¡