Announcements Trials
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Phase

Phase 2 1

Status

Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Endometrial Neoplasms 10Uterine Cervical Neoplasms 5Ovarian Neoplasms 5Neoplasm Metastasis 5Pancreatic Neoplasms 4Breast Neoplasms 4Squamous Cell Carcinoma of Head and Neck 3Neoplasms 3Triple Negative Breast Neoplasms 2Rectal Neoplasms 2Lung Neoplasms 2Locally Advanced Rectal Cancer (LARC) 2Head and Neck Neoplasms 2Fallopian Tube Neoplasms 2Colonic Neoplasms 2Carcinoma, Neuroendocrine 2Vulvar Neoplasms 1Vaginal Neoplasms 1Uterine Neoplasms 1Small Cell Lung Carcinoma 1Skin Neoplasms 1Sarcoma 1Recurrence 1Rectal Adenocarcinoma with Mismatch-repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) 1Penile Neoplasms 1Pathologic Complete Response 1Ovarian Carcinosarcoma 1Oropharyngeal Neoplasms 1Neoplasms, Second Primary 1Mouth Neoplasms 1

Interventions

Radiosurgery 114Temozolomide 104Bevacizumab 71Radiotherapy 67Magnetic Resonance Spectroscopy 67Carboplatin 29pembrolizumab 28Irinotecan 26Surgical Procedures, Operative 25Radiation 23Nivolumab 23Etoposide 22Magnetic Resonance Imaging 21Ipilimumab 21Erlotinib Hydrochloride 21Cyclophosphamide 21Surveys and Questionnaires 19Aminolevulinic Acid 18Specimen Handling 16Pemetrexed 16Mental Status and Dementia Tests 16Cisplatin 16Carmustine 15Topotecan 14Trastuzumab 13Saline Solution 12Neuropsychological Tests 12Gefitinib 11Filgrastim 11Drug Therapy 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
OTHER × Brain Neoplasms × dostarlimab × Clear all
NCT05700721 2026-02-05

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

M.D. Anderson Cancer Center

Phase 2 Recruiting
120 enrolled
CNS

Brain Neoplasms

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