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Phase

Phase EARLY_PHASE1 1Phase 1/2 1Phase 1 1

Status

Withdrawn 1Terminated 1Completed 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Leukemia, Myeloid, Acute 228Leukemia, Lymphocytic, Chronic, B-Cell 211Leukemia 201Myelodysplastic Syndromes 184Precursor Cell Lymphoblastic Leukemia-Lymphoma 172Lymphoma 147Lymphoma, Non-Hodgkin 141Multiple Myeloma 130Hodgkin Disease 121Lymphoma, Follicular 110Lymphoma, Mantle-Cell 107Lymphoma, Large B-Cell, Diffuse 95Lymphoma, B-Cell, Marginal Zone 88Myeloproliferative Disorders 86Congenital Abnormalities 84Burkitt Lymphoma 84Leukemia, Myelomonocytic, Chronic 77Leukemia, Myelogenous, Chronic, BCR-ABL Positive 75Leukemia, Myeloid, Chronic-Phase 74Leukemia, Myeloid, Accelerated Phase 72Recurrence 62Melanoma 61Lymphoma, Large-Cell, Immunoblastic 60Anemia, Refractory, with Excess of Blasts 60Primary Myelofibrosis 55Neoplasms, Plasma Cell 55Waldenstrom Macroglobulinemia 54Blast Crisis 54Hematologic Neoplasms 44Lymphoma, T-Cell, Cutaneous 42

Interventions

Temozolomide 162Radiosurgery 114Radiotherapy 99Bevacizumab 95Magnetic Resonance Spectroscopy 64Carboplatin 48Etoposide 34Surgical Procedures, Operative 33Irinotecan 33pembrolizumab 32Nivolumab 32Cyclophosphamide 32Erlotinib Hydrochloride 31Radiation 29Carmustine 28Cisplatin 25Lomustine 24Trastuzumab 23Ipilimumab 23Filgrastim 23Vincristine 20Mental Status and Dementia Tests 20Aminolevulinic Acid 19Topotecan 18Pemetrexed 18Capecitabine 18Specimen Handling 17Sorafenib 15Radiotherapy, Intensity-Modulated 15Imatinib Mesylate 15

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Brain Neoplasms × fludarabine phosphate × Clear all
NCT04521946 2024-10-26

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

M.D. Anderson Cancer Center

Phase 1 Withdrawn
CNS

Choroid Plexus Carcinoma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT02774291 2023-08-04

Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes

Albert Einstein College of Medicine

Phase EARLY_PHASE1 Terminated
3 enrolled 6 charts
CNS

Brain Neoplasms, Neoplasm Metastasis

NCT01454596 2019-08-21

CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII

National Institutes of Health Clinical Center (CC)

Phase 1/2 Completed
18 enrolled 25 charts
CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

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