NCT05593094 2026-02-25A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid TumorsHoffmann-La RochePhase 1/2 Active not recruiting210 enrolled
NCT04760431 2021-06-02TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN)Second Affiliated Hospital, School of Medicine, Zhejiang UniversityPhase 2 Unknown120 enrolled
NCT02598427 2018-02-28Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast CancerDuke UniversityPhase 1 Terminated1 enrolled