Announcements Trials

Browse Landscape Eligibility

Clinical Trials

1 trials

Recent Start date Enrollment

Phase 1 × Brain Neoplasms × sotorasib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Carcinoma, Non-Small-Cell Lung 6 Neoplasm Metastasis 2 Lung Neoplasms 2 Advanced Solid Tumors 2 Thoracic Neoplasms 1 Noonan Syndrome 1 Non-small Cell Lung Cancer Metastatic 1 Neoplasms 1 Healthy Participants 1 Brain Neoplasms 1 Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation 1 Advanced Solid Tumor 1 Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation 1

Interventions

Temozolomide 38 Radiotherapy 21 Radiosurgery 21 Irinotecan 11 Cyclophosphamide 11 Radiation 10 Magnetic Resonance Spectroscopy 10 Etoposide 10 Surgical Procedures, Operative 9 Erlotinib Hydrochloride 9 Carmustine 9 Filgrastim 8 Carboplatin 8 pembrolizumab 7 Bevacizumab 7 Vincristine 6 Sorafenib 6 O(6)-benzylguanine 6 Nivolumab 6 Flucytosine 6 Aminolevulinic Acid 6 temsirolimus 5 sargramostim 5 Vorinostat 5 Trastuzumab 5 Topotecan 5 Imatinib Mesylate 5 Granulocyte Colony-Stimulating Factor 5 Everolimus 5 cediranib 4

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06807619 2025-05-22

A Study of Sotorasib in People With Brain Tumors

Memorial Sloan Kettering Cancer Center

Phase 1 Recruiting

Brain Neoplasms

Data powered by HemOnc (CC BY 4.0) Colophon ⚡