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Interventional × Brain Neoplasms × sotorasib × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Carcinoma, Non-Small-Cell Lung 23 Lung Neoplasms 11 Neoplasms 5 Colorectal Neoplasms 5 Neoplasm Metastasis 4 Advanced Solid Tumors 3 Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation 2 Venous Thromboembolism 1 Thoracic Neoplasms 1 Solid Tumor, Adult 1 Solid Tumor 1 Respiratory Tract Neoplasms 1 Respiratory Tract Diseases 1 Pancreatic Neoplasms 1 Ovarian Neoplasms 1 Noonan Syndrome 1 Non-small Cell Lung Cancer Metastatic 1 Non Small Lung Cancer 1 Neoplasms by Site 1 Lung Diseases 1 KRAS p.G12C Mutant Advanced Solid Tumors 1 KRAS p, G12c Mutated /Advanced Metastatic NSCLC 1 Hereditary Sensory and Autonomic Neuropathies 1 Healthy Participants 1 Fallopian Tube Neoplasms 1 Endometrial Neoplasms 1 Efficacy 1 Carcinoma 1 Bronchial Neoplasms 1 Brain Neoplasms 1

Interventions

Temozolomide 161 Radiosurgery 114 Radiotherapy 99 Bevacizumab 95 Magnetic Resonance Spectroscopy 64 Carboplatin 48 Etoposide 34 Surgical Procedures, Operative 33 Irinotecan 33 pembrolizumab 32 Nivolumab 32 Cyclophosphamide 32 Erlotinib Hydrochloride 31 Radiation 29 Carmustine 28 Cisplatin 25 Lomustine 24 Trastuzumab 23 Ipilimumab 23 Filgrastim 23 Vincristine 20 Mental Status and Dementia Tests 20 Aminolevulinic Acid 19 Topotecan 18 Pemetrexed 18 Capecitabine 18 Specimen Handling 17 Sorafenib 15 Radiotherapy, Intensity-Modulated 15 Imatinib Mesylate 15

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06807619 2025-05-22

A Study of Sotorasib in People With Brain Tumors

Memorial Sloan Kettering Cancer Center

Phase 1 Recruiting

Brain Neoplasms

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