Clinical Trials Browser

Brain Diseases, Brain Neoplasms, Breast Diseases, Breast Neoplasms, Central Nervous System Diseases, Neoplasms, Neoplasms by Site, Central Nervous System Neoplasms

NCT03449238 2026-03-30

Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

Phase 1/2 Recruiting

41 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT04085887 2026-03-20

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Phase 1/2 Recruiting

12 enrolled

CNS

Brain Neoplasms

NCT05789589 2026-03-04

ADORATION

Phase 1/2 Recruiting

46 enrolled

CNS

Brain Neoplasms, Neoplasm Metastasis, Neoplasms

NCT06047379 2026-03-02

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Phase 1/2 Recruiting

134 enrolled

CNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Astrocytoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Glioblastoma, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Central Nervous System Neoplasms, Small Cell Lung Carcinoma

NCT03510208 2026-02-09

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

Phase 1/2 Recruiting

46 enrolled

CNS

Brain Neoplasms, Glioma

NCT04923542 2026-02-06

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

Phase 1/2 Recruiting

31 enrolled

CNS

Brain Neoplasms

NCT05588453 2026-01-12

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Phase 1/2 Recruiting

30 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT04711824 2025-12-23

SOLARA

Phase 1/2 Recruiting

41 enrolled

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT06194929 2025-12-03

DETERMINE

Phase 1/2 Recruiting

33 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT07206498 2025-11-28

WAYWIN103

Phase 1/2 Recruiting

48 enrolled

CNSThoracic

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT04977375 2025-09-03

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

Phase 1/2 Recruiting

10 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms

NCT06907043 2025-08-19

EIK1004-001

Phase 1/2 Recruiting

130 enrolled

CNS

Brain Neoplasms

NCT05535413 2025-04-25

UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases

Phase 1/2 Recruiting

30 enrolled

CNS

Brain Neoplasms

NCT02861898 2025-04-09

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Phase 1/2 Recruiting

33 enrolled

CNS

Brain Neoplasms, Glioblastoma

NCT03213002 2025-04-09

CAPTEM

Phase 1/2 Recruiting

67 enrolled

CNS

Brain Neoplasms, Glioblastoma, Neoplasms

NCT01906385 2025-03-26

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

Phase 1/2 Recruiting

55 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma

NCT06640582 2024-11-05

BAH2472

Phase 1/2 Recruiting

85 enrolled

CNS

Brain Neoplasms, Glioblastoma, Glioma, Meningioma

NCT06243003 2024-02-07

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Phase 1/2 Recruiting

56 enrolled

CNS

Brain Neoplasms

Clinical Trials

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

DURABLE

ELECTRA

Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

ADORATION

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

SOLARA

DETERMINE

WAYWIN103

Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma

EIK1004-001

UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

CAPTEM

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

BAH2472

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases