Clinical Trials
60 trialsNCT05341349 2026-04-23
Stereotactic Radiosurgery and Immune Checkpoint Inhibitors With NovoTTF-200M for the Treatment of Melanoma Brain Metastases
Emory University
Phase 1 Terminated
NCT06193174 2026-01-22
Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)
University of Alabama at Birmingham
Phase 1 Terminated
NCT05553522 2025-12-31
Tucatinib, Trastuzumab, and Capecitabine With SRS for Brain Metastases From HER-2 Positive Breast Cancer
Baptist Health South Florida
Phase 1 Terminated
NCT03396575 2025-10-29
BRAVO
University of Florida
Phase 1 Terminated
NCT04543188 2025-10-23
A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement
Pfizer
Phase 1 Terminated
NCT05388877 2025-08-19
E6201 and Dabrafenib for the Treatment of Central Nervous System Metastases From BRAF V600 Mutated Metastatic Melanoma
Mayo Clinic
Phase 1 Terminated
NCT01324635 2025-05-02
Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors
Thomas Jefferson University
Phase 1 Terminated
NCT01551680 2025-02-13
RAPIBE
Institut du Cancer de Montpellier - Val d'Aurelle
Phase 1 Terminated
NCT05241873 2025-02-10
(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
Blueprint Medicines Corporation
Phase 1 Terminated
NCT04771897 2024-12-20
KONQUER
Bexion Pharmaceuticals, Inc.
Phase 1 Terminated
NCT05831995 2024-12-06
Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.
ABM Therapeutics Corporation
Phase 1 Terminated
NCT04525014 2024-10-31
PIRATE
EpicentRx, Inc.
Phase 1 Terminated
NCT01246869 2024-10-01
Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water
University of Utah
Phase 1 Terminated
NCT03539731 2024-08-12
[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers
Stanford University
Phase 1 Terminated
NCT03250299 2024-06-24
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Basilea Pharmaceutica
Phase 1 Terminated
NCT04901806 2024-03-28
Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors
Pyramid Biosciences
Phase 1 Terminated
NCT03705351 2024-03-04
Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM
Providence Health & Services
Phase 1 Terminated
NCT04187872 2023-12-27
TORCH
University of Florida
Phase 1 Terminated
NCT00089245 2023-12-26
Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer
Y-mAbs Therapeutics
Phase 1 Terminated
NCT03332589 2022-05-20
E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS)
Spirita Oncology, LLC
Phase 1 Terminated
NCT01058850 2021-09-27
Phase I Rindopepimut After Conventional Radiation in Children w/ Diffuse Intrinsic Pontine Gliomas
Stanford University
Phase 1 Terminated
NCT03967093 2021-07-22
KOURAGE
Bexion Pharmaceuticals, Inc.
Phase 1 Terminated
NCT02187822 2021-02-04
Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Terminated
NCT04327011 2020-03-30
A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
Tocagen Inc.
Phase 1 Terminated
NCT00108056 2019-12-05
Enzastaurin to Treat Recurrent Brain Tumor
National Institutes of Health Clinical Center (CC)
Phase 1 Terminated
NCT00734526 2018-11-09
Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT00038389 2018-11-01
Study of Vioxx and Radiation Therapy for Brainstem Glioma
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT01103375 2018-08-01
Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma
Wake Forest University Health Sciences
Phase 1 Terminated
NCT00880061 2018-07-05
An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma
National Institutes of Health Clinical Center (CC)
Phase 1 Terminated
NCT02201563 2018-06-25
Minocycline Therapy for Management of Adverse Radiation Effects
University of Pittsburgh
Phase 1 Terminated
NCT02598427 2018-02-28
Intrathecal Pertuzumab and Trastuzumab in Patients With New Untreated Asymptomatic or Low Symptomatic Brain Metastasis in HER2 Positive Breast Cancer
Duke University
Phase 1 Terminated
NCT00003926 2017-11-29
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors
Masonic Cancer Center, University of Minnesota
Phase 1 Terminated
NCT01508104 2017-08-23
Safety Study of BEZ235 With Everolimus in Subjects With Advanced Solid Tumors
University of Cincinnati
Phase 1 Terminated
NCT01526837 2017-07-12
Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence
Brain & Spine Surgeons of New York
Phase 1 Terminated
NCT02648633 2017-05-31
Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma
University of Virginia
Phase 1 Terminated
NCT00253721 2017-04-21
Melphalan With BBBD in Treating Patients With Brain Malignancies
OHSU Knight Cancer Institute
Phase 1 Terminated
NCT00769093 2017-04-21
Assessing Dynamic Magnetic Resonance (MR) Imaging in Patients With Recurrent High Grade Glioma Receiving Chemotherapy
OHSU Knight Cancer Institute
Phase 1 Terminated
NCT01902771 2017-03-10
Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
University of Miami
Phase 1 Terminated
NCT00437957 2017-02-23
Phase I Study of Temozolomide, Valproic Acid and Radiation Therapy in Patients With Brain Metastases
H. Lee Moffitt Cancer Center and Research Institute
Phase 1 Terminated
NCT01148966 2017-02-15
Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors
University of Washington
Phase 1 Terminated
NCT01502605 2017-01-05
Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 1 Terminated
NCT00805103 2016-12-29
HF-SRT
University Health Network, Toronto
Phase 1 Terminated
NCT02370563 2016-09-02
PET Imaging of Intracranial Cancers With 18F-FSPG
Lantheus Biosciences Ltd.
Phase 1 Terminated
NCT00512460 2016-05-16
RTA 744 Injection in Patients With Leptomeningeal Disease
M.D. Anderson Cancer Center
Phase 1 Terminated
NCT01122888 2015-04-28
Cilengitide and Sunitinib Malate in Treating Patients With Advanced Solid Tumors or Glioblastoma Multiforme
National Cancer Institute (NCI)
Phase 1 Terminated
NCT01009866 2015-03-20
MR1-1
Duke University
Phase 1 Terminated
NCT00023634 2015-03-06
S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer
SWOG Cancer Research Network
Phase 1 Terminated
NCT01378481 2014-12-23
High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma
National Cancer Institute (NCI)
Phase 1 Terminated
NCT01018836 2014-05-02
Riluzole and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
Rutgers, The State University of New Jersey
Phase 1 Terminated
NCT01322100 2013-07-31
Electrochemotherapy as a Palliative Treatment for Brain Metastases
Copenhagen University Hospital at Herlev
Phase 1 Terminated