Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
Completed
76 enrolled
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors
Phase 1 Completed
16 enrolled
Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors
Phase 2 Completed
36 enrolled
Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases
Phase 2 Completed
344 enrolled 11 charts
Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases
Completed
35 enrolled
Natural History of and Specimen Banking for People With Tumors of the Central Nervous System
Completed
1,214 enrolled
Rare CNS Tumors Outcomes &Risk
Completed
326 enrolled
Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients
Phase 2 Completed
61 enrolled 20 charts
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
Phase 1 Completed
17 enrolled
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
Phase 1 Completed
3 enrolled 12 charts
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab
Phase 2 Completed
35 enrolled 13 charts
Carboplatin and Bevacizumab for Recurrent Ependymoma
Phase 2 Completed
35 enrolled 17 charts
Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers
Phase 2 Completed
133 enrolled
Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
Phase 1 Completed
29 enrolled
Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments
Completed
598 enrolled
Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade
Phase 1 Completed
21 enrolled 9 charts
Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors
Phase 1 Completed
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma
Phase 2 Completed
7 enrolled 20 charts
Stereotactic Radiosurgery in Treating Patients With Brain Tumors
Phase 1 Completed
Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer
Phase 2 Completed
143 enrolled 24 charts
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers
Phase NA Completed
10 enrolled 16 charts
Comparison of PET and Proton MRS Imaging to Evaluate Pediatric Brain Tumor Activity
Completed
79 enrolled
Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumors
Phase 2 Completed
137 enrolled 13 charts
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas
Phase 1/2 Completed
86 enrolled 24 charts
Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas
Phase 1 Completed
29 enrolled
Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma
Phase 1/2 Completed
36 enrolled 15 charts
Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases
Phase 3 Completed
332 enrolled
Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare Diseases
Completed
482 enrolled
A Prospective Cohort Study of Occupational Exposures and Cancer Risk Among Women
Completed
75,366 enrolled
Study of Health Effects of Cosmetic Breast Augmentation
Completed
17,424 enrolled
Cancer and Other Disease Risks in U.S. Nuclear Medicine Technologists
Completed
229 enrolled
Early Life Exposures in Agriculture
Completed
60,000 enrolled
AZD7451 for Recurrent Gliomas
Phase 1 Completed
14 enrolled
Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development
Completed
20 enrolled
AZD8055 for Adults With Recurrent Gliomas
Phase 1 Completed
22 enrolled
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors
Phase 1 Completed
9 enrolled
ZD6474 to Treat Advanced Brain Cancer in Patients
Phase 1 Completed
83 enrolled
CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
Phase 1/2 Completed
18 enrolled 25 charts
Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Phase 2 Completed
64 enrolled 12 charts
Phase I Trial of Tariquidar (XR9576) in Combination With Doxorubicin, Vinorelbine, or Docetaxel in Pediatric Patients With Solid Tumors
Phase 1 Completed
29 enrolled
A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors
Completed
40 enrolled
(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy
Completed
50 enrolled
Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma
Phase 2 Completed
58 enrolled 11 charts
Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma
Phase 1/2 Completed
115 enrolled 13 charts
Bevacizumab and Irinotecan or Temozolomide in Treating Patients With Recurrent or Refractory Glioblastoma Multiforme or Gliosarcoma
Phase 2 Completed
123 enrolled 16 charts
GW572016 to Treat Recurrent Malignant Brain Tumors
Phase 2 Completed
9 enrolled
Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
Phase 1 Completed
9 enrolled
Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Phase 1/2 Completed
92 enrolled 24 charts
Bevacizumab With or Without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients With Recurrent Glioblastoma Multiforme
Phase 1/2 Completed
116 enrolled 17 charts
A Case-Referent Study of Brain Tumors in Adults
Completed
1,581 enrolled