Clinical Trials Browser

Completed × Interventional × Brain Neoplasms × Clear all

NCT01875601 2026-05-22

NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumors

Phase 1 Completed

Brain Neoplasms, Neuroblastoma, Sarcoma

NCT04895592 2026-05-14

Radiosurgery Before Surgery for the Treatment of Brain Metastases

Phase EARLY_PHASE1 Completed

Brain Neoplasms, Neoplasm Metastasis

NCT01705548 2026-05-07

Hypofractionated Stereotactic Radiosurgery in Treating Patients With Large Brain Metastasis

Phase NA Completed

24 enrolled 16 charts

Brain Neoplasms

NCT05865990 2026-05-04

TUXEDO-3

Phase 2 Completed

Brain Neoplasms, Breast Neoplasms, Meningeal Neoplasms

NCT04859543 2026-05-01

PPROSPERITIT

Phase NA Completed

Brain Neoplasms, Neoplasms, Central Nervous System Neoplasms

NCT03680144 2026-04-24

Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases

Phase NA Completed

Brain Neoplasms

NCT01503086 2026-04-23

Computer Training Program for Younger Patients With a Brain Tumor Who Underwent Radiation Therapy

Phase NA Completed

45 enrolled 10 charts

Brain Neoplasms

NCT02250755 2026-04-22

METAPERF

Phase NA Completed

Brain Neoplasms

NCT04817254 2026-04-17

Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00814021 2026-04-15

Sunitinib in Treating Patients With Kidney Cancer That Has Spread to the Brain

Phase 2 Completed

CNSGenitourinary

Brain Neoplasms, Carcinoma, Renal Cell, Kidney Neoplasms, Neoplasm Metastasis

NCT03115398 2026-04-13

A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery

Phase NA Completed

CNSGastrointestinalGynecologicHead & NeckThoracic

Brain Neoplasms, Uterine Cervical Neoplasms, Gastrointestinal Neoplasms, Head and Neck Neoplasms, Lung Neoplasms

NCT04988750 2026-04-13

Evaluate the Safety and Preliminary Efficacy of the Combination of NaviFUS System With Re-irradiation for rGBM Patients

Phase NA Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT04446416 2026-04-09

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

Phase NA Completed

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Neoplasms, Nerve Tissue

NCT02153957 2026-04-08

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Phase 2 Completed

Brain Neoplasms, Motor Activity

NCT02595905 2026-04-08

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Phase 2 Completed

344 enrolled 11 charts

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT05704933 2026-04-06

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

Phase EARLY_PHASE1 Completed

CNSDermatologic

Brain Neoplasms, Melanoma

NCT00850278 2026-04-02

FLT

Phase NA Completed

Brain Neoplasms, Neoplasms

NCT04890028 2026-03-31

DOPACER

Phase NA Completed

BreastCNSDermatologicThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms, Melanoma

NCT04266665 2026-03-25

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

Phase 4 Completed

Neuroinflammatory Diseases, Hypoxia, Brain Neoplasms

NCT04545814 2026-03-24

Analyzing Preoperative Stereotactic Radiosurgery With Gamma Knife Icon for Brain Metastases

Phase NA Completed

11 enrolled 11 charts

Brain Neoplasms

NCT03714243 2026-03-20

BBBD

Phase NA Completed

Brain Neoplasms, Breast Neoplasms

NCT03475186 2026-03-13

Testing Ramipril to Prevent Memory Loss in People With Glioblastoma

Phase 2 Completed

75 enrolled 47 charts

Brain Neoplasms, Glioblastoma, Cognitive Dysfunction

NCT04044937 2026-03-11

UC-GlioFET

Phase 2 Completed

Brain Neoplasms, Glioblastoma

NCT04301089 2026-03-11

Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients

Phase 2 Completed

61 enrolled 20 charts

Anxiety Disorders, Brain Neoplasms

NCT02858869 2026-03-09

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

Phase 1 Completed

25 enrolled 14 charts

CNSDermatologicThoracic

Uveal Melanoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT02303678 2026-03-06

D2C7 for Adult Patients With Recurrent Malignant Glioma

Phase 1 Completed

Brain Neoplasms, Glioma

NCT03368625 2026-03-04

NASRS

Phase NA Completed

Brain Neoplasms

NCT03719768 2026-03-02

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

Phase 1 Completed

Brain Neoplasms, Meningeal Neoplasms, Meningeal Carcinomatosis

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Phase 1/2 Completed

47 enrolled 36 charts

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT02669173 2026-02-23

Capecitabine + Bevacizumab in Patients With Recurrent Glioblastoma

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Recurrence

NCT04268979 2026-02-20

Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator

Phase NA Completed

296 enrolled 11 charts

Brain Neoplasms

NCT07405047 2026-02-12

Fractionated Stereotactic Radiotherapy for Limited Small Volume Brain Metastases

Phase NA Completed

Brain Neoplasms

NCT02909777 2026-02-11

Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma

Phase 1 Completed

Brain Neoplasms, Lymphoma, Neuroblastoma

NCT04173104 2026-02-09

PET and MRI Imaging of Brain Tumors Using [18F]PARPi

Phase EARLY_PHASE1 Completed

Brain Neoplasms

NCT05427838 2026-02-04

STEDI2

Phase NA Completed

Brain Neoplasms, Skull Fractures, Intracranial Hemorrhages, Stroke

NCT06057168 2026-01-29

GDX-44-016

Phase 3 Completed

138 enrolled 7 charts

Brain Neoplasms

NCT03262636 2026-01-23

TumorGlow(TM)

Phase 1 Completed

Brain Neoplasms

NCT03873818 2026-01-09

Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain

Phase 2 Completed

24 enrolled 13 charts

CNSDermatologic

Brain Neoplasms, Melanoma

NCT02709226 2025-12-31

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT06322342 2025-12-26

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

Phase 2 Completed

Neuroinflammatory Diseases, Brain Neoplasms, Glioma, Meningioma, Multiple Sclerosis, Neoplasms, Neurilemmoma, Neurofibroma, Neuroma, Acoustic, Central Nervous System Neoplasms

NCT05465343 2025-12-19

Furmonertinib in EGFR-Mutant NSCLC With Brain Metastases (iFORCE)

Phase 2 Completed

Brain Neoplasms

NCT03638167 2025-12-17

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

Phase 1 Completed

Choroid Plexus Carcinoma, Brain Neoplasms, Ependymoma, Glioma, Medulloblastoma, Neoplasms, Germ Cell and Embryonal, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT04738162 2025-12-10

Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors

Phase 2 Completed

Brain Neoplasms

NCT03807765 2025-12-04

Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

Phase 1 Completed

Brain Neoplasms, Breast Neoplasms

NCT04503772 2025-12-04

STEP

Phase 2 Completed

Brain Neoplasms

NCT05848050 2025-11-24

METALIQ

Phase NA Completed

Brain Neoplasms

NCT05762172 2025-11-18

DYNDOPATEP

Phase NA Completed

Brain Neoplasms

NCT03412812 2025-11-04

RAD1705

Phase NA Completed

13 enrolled 9 charts

Brain Neoplasms

NCT02831959 2025-10-31

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Phase 3 Completed

Brain Neoplasms, Carcinoma, Non-Small-Cell Lung

NCT06171945 2025-10-27

AYAConnect

Phase NA Completed

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckLymphoidOtherOther hematologic neoplasmSarcoma

Psychological Well-Being, Urinary Bladder Neoplasms, Bone Neoplasms, Brain Neoplasms, Breast Neoplasms, Uterine Cervical Neoplasms, Colonic Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Kidney Neoplasms, Leukemia, Liver Neoplasms, Lymphoma, Non-Hodgkin, Melanoma, Motor Activity, Mouth Neoplasms, Neoplasms, Obesity, Pancreatic Neoplasms, Pharyngeal Neoplasms, Rectal Neoplasms, Sarcoma, Testicular Neoplasms, Thyroid Neoplasms, Weight Loss, Endometrial Neoplasms, Overweight