NCT07416188 2026-04-16
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
National Institutes of Health Clinical Center (CC)
Phase 1/2 Not yet recruiting
Clinical Trials
80 trialsNCT07505979 2026-04-13
SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases
National Taiwan University Hospital
Phase 2 Not yet recruiting
NCT07520370 2026-04-09
Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor
Beijing Tiantan Hospital
Phase NA Not yet recruiting
NCT07206849 2026-04-08
Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)
Nationwide Children's Hospital
Phase 2 Not yet recruiting
NCT07248228 2026-04-08
Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)
Case Comprehensive Cancer Center
Phase 2 Not yet recruiting
NCT07512154 2026-04-07
Precision Radiotherapy Enabled by Molecular MRI
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase NA Not yet recruiting
NCT07449481 2026-04-01
A Phase II Clinical Study of Utidelone and Bevacizumab With or Without Etoposide in Patients With Brain Metastases From Malignant Solid Tumors
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Not yet recruiting
NCT06630338 2026-03-27
Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness Measurements
Mayo Clinic
Not yet recruiting
NCT07496073 2026-03-27
A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN）
Tianjin Medical University Cancer Institute and Hospital
Phase 1 Not yet recruiting
NCT07492680 2026-03-25
A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
Bristol-Myers Squibb
Phase 2 Not yet recruiting
NCT07493447 2026-03-25
Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT07467109 2026-03-19
A Study to Evaluate the Safety and Efficacy of Intracranial Venous Blood Sampling for Liquid Biopsy in the Diagnosis of Brain Cancers
M.D. Anderson Cancer Center
Not yet recruiting
NCT06667726 2026-03-16
An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors
Mayo Clinic
Phase 2 Not yet recruiting
NCT07470606 2026-03-13
MemoryRT
The University of Texas Health Science Center at San Antonio
Phase 2 Not yet recruiting
NCT07039760 2026-03-11
Asciminib With or Without Sildenafil for Brain Tumors
Washington University School of Medicine
Phase EARLY_PHASE1 Not yet recruiting
NCT07462507 2026-03-10
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Washington University School of Medicine
Phase 2 Not yet recruiting
NCT07458113 2026-03-09
BERLIN
Yale University
Phase 2 Not yet recruiting
NCT07454668 2026-03-06
Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases
Baptist Health South Florida
Phase 1 Not yet recruiting
NCT07402343 2026-03-04
T-BRAIN
Maastricht University Medical Center
Phase 2 Not yet recruiting
NCT07437820 2026-03-04
NeoSRS
GCS Ramsay Santé pour l'Enseignement et la Recherche
Phase NA Not yet recruiting
NCT07210632 2026-02-27
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Vanderbilt-Ingram Cancer Center
Phase EARLY_PHASE1 Not yet recruiting
NCT07439172 2026-02-27
PRC
The Cooper Health System
Phase 2 Not yet recruiting
NCT07428616 2026-02-24
A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
Exelixis
Phase 2 Not yet recruiting
NCT07271966 2026-02-20
BALANCE
Duke University
Phase NA Not yet recruiting
NCT07384884 2026-02-19
SLITT-GBM
King's College Hospital NHS Trust
Phase NA Not yet recruiting
NCT07418775 2026-02-18
Tumor Genomics, Individual Risk Factors, and External Drivers of Health on Health Outcomes for Patients With Meningioma
University of California, San Francisco
Not yet recruiting
NCT07415668 2026-02-17
MENTOR
Insel Gruppe AG, University Hospital Bern
Phase NA Not yet recruiting
NCT07278440 2026-02-13
An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial
OHSU Knight Cancer Institute
Phase NA Not yet recruiting
NCT07398066 2026-02-09
DEX-NEURO
University of Malaya
Phase NA Not yet recruiting
NCT07390539 2026-02-05
B7-H3.CD28Z.CART in CNS Neoplasms
Dana-Farber Cancer Institute
Phase 1 Not yet recruiting
NCT07376304 2026-01-29
BrainUS-AI
Hospital del Rio Hortega
Phase 3 Not yet recruiting
NCT07365410 2026-01-26
Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study
Tianjin Medical University Cancer Institute and Hospital
Phase 2 Not yet recruiting
NCT06907485 2026-01-21
A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients
University of Pittsburgh
Phase 2 Not yet recruiting
NCT07343479 2026-01-15
Sacituzumab Tirumotecan Plus Third-Generation TKI With/Without Radiotherapy for EGFR-Mutant NSCLC Brain Metastases
Zhejiang Cancer Hospital
Phase 2 Not yet recruiting
NCT04745156 2026-01-12
A Study Using Brain Stimulation and Behavioral Therapy to Increase Extent of Resection in Low-Grade Gliomas
Medical College of Wisconsin
Phase NA Not yet recruiting
NCT07329634 2026-01-09
RENESANS
Prof. Franciszek Lukaszczyk Memorial Oncology Center
Phase 3 Not yet recruiting
NCT07331064 2026-01-09
GABRIEL
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT07313709 2026-01-02
Measuring the Feasibility and Effect of a Virtual Reality Cognitive Training Intervention for Brain Cancer Survivors.
University of Cincinnati
Phase NA Not yet recruiting
NCT07264023 2025-12-16
Correlation Between Nutritional Status of Childhood Neurological Tumors and Quality of Life
Nanfang Hospital, Southern Medical University
Not yet recruiting
NCT07286396 2025-12-16
Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients
Tanta University
Not yet recruiting
NCT07274397 2025-12-10
EARLYBRAINPET
Beta Emitting Accurate Monitored Systems
Phase NA Not yet recruiting
NCT07254845 2025-11-28
A PROSPECTIVE, SINGLE-CENTERED, ASSESSOR-BLINDED STUDY TO EVALUATE THE CLINICAL EFFICACY OF THE PROPOSED CELL/TISSUE HISTOPATHOLOGY PROCESSOR CCELL (CONFOCAL FLUORESCENCE ENDOMICROSCOPY) FOR INTRAOPERATIVE DIAGNOSIS IN BRAIN TUMORS
VPIX Medical
Phase 1 Not yet recruiting
NCT07226466 2025-11-10
Evaluating Biomarkers of Cognitive Dysfunction in Patients With Cancer
University of California, San Francisco
Not yet recruiting
NCT07199413 2025-09-30
Allogeneic, Antigen-Presenting, GM-CSF-secreting, SV-BR-1-GM Whole Cell-Therapeutic Vaccine and Immunotherapy: A Phase I Pilot Safety and Feasibility Study for Solid Tumor Patients With CNS Metastases
Medical College of Wisconsin
Phase 1 Not yet recruiting
NCT07197008 2025-09-29
Sacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain Metastasis
Sun Yat-sen University
Phase 2 Not yet recruiting
NCT07185958 2025-09-22
DART
Aalborg University Hospital
Not yet recruiting
NCT07177950 2025-09-17
A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases
Peking University Cancer Hospital & Institute
Phase 1/2 Not yet recruiting
NCT07170436 2025-09-12
BRAIN-MAP
University Hospital, Toulouse
Phase NA Not yet recruiting
NCT07167134 2025-09-11
SISMIC
Centre Paul Strauss
Phase 3 Not yet recruiting
NCT06455189 2025-08-13
Magnetic Resonance Fingerprinting Guided Extended Resection in Glioblastomas
Case Comprehensive Cancer Center
Phase 1 Not yet recruiting