Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Breast 2Gastrointestinal 1

Conditions

Breast Neoplasms 7Neoplasms 4Ovarian Neoplasms 2Breast Neoplasms, Male 2Waldenstrom Macroglobulinemia 1Stomach Neoplasms 1Solid Tumors 1Sezary Syndrome 1Recurrence 1Prostatic Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pdgfra-Associated Chronic Eosinophilic Leukemia 1Pancreatic Neoplasms 1Myeloproliferative Syndrome, Transient 1Mycosis Fungoides 1Melanoma 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Anaplastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1Lymphoma, Extranodal NK-T-Cell 1Lymphoma, B-Cell, Marginal Zone 1Locally Advanced or Metastatic Solid Tumors 1Leukemia, Prolymphocytic 1Leukemia, Neutrophilic, Chronic 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Myelomonocytic, Chronic 1Leukemia, Myeloid, Chronic-Phase 1Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 1Leukemia, Myeloid, Acute 1

Interventions

Trastuzumab 8Paclitaxel 7Taxes 6Lapatinib 6Docetaxel 5veliparib 3Tamoxifen 32,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 3sargramostim 2liposomal doxorubicin 2ixabepilone 2cediranib 2Vorinostat 2Vinorelbine 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl-6-(5-((methylsulfonyl)ethyl)aminomethyl)-2-furyl)-4-quinazolinamine 2Mifepristone 2MK 2206 2Interleukin-12 Subunit p35 2Interleukin-12 2Granulocyte-Macrophage Colony-Stimulating Factor 2Goserelin 2Gemcitabine 2Filgrastim 2Everolimus 2Erlotinib Hydrochloride 2Doxorubicin 2Cyclophosphamide 2Cisplatin 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Breast Neoplasms, Male × MK 2206 × Clear all
NCT01245205 2014-10-23

Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast Cancer

National Cancer Institute (NCI)

Phase 1 Completed
28 enrolled
Breast

Breast Neoplasms, Breast Neoplasms, Male

NCT01705340 2013-09-30

Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By Surgery

National Cancer Institute (NCI)

Phase 1 Terminated
60 enrolled
BreastGastrointestinal

Breast Neoplasms, Esophageal Neoplasms, Stomach Neoplasms, Breast Neoplasms, Male

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