Announcements Trials
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Phase

Phase 2 15Phase 1 14Phase 3 6Phase 1/2 5Phase EARLY_PHASE1 1

Status

Terminated 2Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 5Gynecologic 1

Conditions

Breast Neoplasms 5Squamous Cell Carcinoma of Head and Neck 2Hereditary Sensory and Autonomic Neuropathies 2Stomach Neoplasms 1Recurrence 1Ovarian Neoplasms 1Oropharyngeal Neoplasms 1Head and Neck Neoplasms 1HER2-positive Metastatic Breast Cancer 1Colorectal Neoplasms 1Carcinoma, Squamous Cell 1Carcinoma 1

Interventions

Trastuzumab 62Paclitaxel 57Cyclophosphamide 44pembrolizumab 34Fulvestrant 34Capecitabine 29Carboplatin 26Docetaxel 23Letrozole 22Doxorubicin 19palbociclib 16abemaciclib 16pertuzumab 15durvalumab 14Filgrastim 13Everolimus 13ribociclib 12Lapatinib 12Gemcitabine 12exemestane 11eribulin 11Vinorelbine 11Albumin-Bound Paclitaxel 11Bevacizumab 10trastuzumab deruxtecan 9neratinib 9fludarabine 9Taxes 9Radiotherapy 9Peripheral Blood Stem Cell Transplantation 9

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1/2 × Breast Neoplasms × Alpelisib × Clear all
NCT01872260 2026-04-01

Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer

Novartis

Phase 1/2 Active not recruiting
255 enrolled
Breast

Breast Neoplasms

NCT05563220 2026-01-06

ELEVATE

Stemline Therapeutics, Inc.

Phase 1/2 Recruiting
435 enrolled
Breast

Breast Neoplasms

NCT03284957 2025-11-24

AMEERA-1

Sanofi

Phase 1/2 Terminated
136 enrolled 60 charts
Breast

Breast Neoplasms

NCT02379247 2022-06-07

BYL719 and Nab-Paclitaxel in Locally Recurrent or Metastatic HER-2 Negative Breast Cancer

University of Kansas Medical Center

Phase 1/2 Completed
43 enrolled 18 charts
Breast

Breast Neoplasms

NCT01708161 2018-09-13

A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors

Novartis

Phase 1/2 Terminated
47 enrolled 23 charts
BreastGynecologic

Breast Neoplasms, Ovarian Neoplasms

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