Announcements Trials
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Phase

Phase 2 4Phase 1 1

Status

Completed 3Terminated 2

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 5

Conditions

Breast Neoplasms 5NSCLC 3Squamous Cell Carcinoma of Head and Neck 2Carcinoma, Non-Small-Cell Lung 2Adenocarcinoma of Lung 2Recurrence 1Lung Neoplasms 1Head and Neck Neoplasms 1HER-2 Positive Advanced Gastric Cancer 1Advanced Solid Tumor 1Advanced Solid Malignancies 1

Interventions

Trastuzumab 597Paclitaxel 562Cyclophosphamide 545Docetaxel 479Capecitabine 388Letrozole 350Fulvestrant 311Doxorubicin 285Carboplatin 277Tamoxifen 257Anastrozole 219exemestane 211Epirubicin 210Radiotherapy 197Bevacizumab 189pertuzumab 177Gemcitabine 163Vinorelbine 162pembrolizumab 161Lapatinib 161palbociclib 152Exercise 132Fluorouracil 118Albumin-Bound Paclitaxel 116eribulin 108Magnetic Resonance Spectroscopy 108130-nm albumin-bound paclitaxel 107Everolimus 103Taxes 96Cisplatin 92

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Breast Neoplasms × HM781-36B × Clear all
NCT03744715 2024-03-05

A Study to Allow Continued Dosing and/or Follow-up of Patients Who Have Had Previous Exposure to Poziotinib

Spectrum Pharmaceuticals, Inc

Phase 2 Terminated
7 enrolled
Breast

Breast Neoplasms

NCT02659514 2022-03-11

Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer

Spectrum Pharmaceuticals, Inc

Phase 2 Completed
67 enrolled 16 charts
Breast

Breast Neoplasms

NCT02418689 2022-01-20

Poziotinib in Patients With HER2+ Recurrent Stage IV BC Who Have Received at Least 2 Prior HER2-directed Regimens

Hanmi Pharmaceutical Company Limited

Phase 2 Completed
106 enrolled
Breast

Breast Neoplasms

NCT03429101 2021-01-15

A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer

Spectrum Pharmaceuticals, Inc

Phase 1 Terminated
6 enrolled
Breast

Breast Neoplasms

NCT02544997 2020-07-07

A Phase II, Single-Arm Trial of Poziotinib as Salvage Treatment in Patients With Metastatic Breast Cancer Who Has HER2 or EGFR Mutation or Activated AR or EGFR Pathway

Samsung Medical Center

Phase 2 Completed
5 enrolled
Breast

Breast Neoplasms

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