Announcements Trials
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Phase

Phase 2 5Phase NA 1

Status

Completed 21Unknown 8Terminated 6Withdrawn 2Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 6

Conditions

Prostatic Neoplasms 8Polycystic Ovary Syndrome 7Carcinoma, Non-Small-Cell Lung 6Breast Neoplasms 6Colorectal Neoplasms 5Lung Neoplasms 4Metabolic Syndrome 3Insulin Resistance 3Adenocarcinoma of Lung 3Lymphoma, Large B-Cell, Diffuse 2Glioblastoma 2Carcinoma, Renal Cell 2pCR Rate 1Weight Gain 1Thyroid Diseases 1Thoracic Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Rectal Neoplasms 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1Obesity 1Non-alcoholic Fatty Liver Disease 1Neoplasms 1Neoplasm Metastasis 1Mouth Neoplasms 1Motor Activity 1Melanoma 1Lymphoma 1Leukoplakia 1Leukemia, Myelomonocytic, Acute 1

Interventions

Trastuzumab 77Capecitabine 59Cyclophosphamide 54Paclitaxel 51Docetaxel 49Letrozole 44Fulvestrant 43Lapatinib 34Doxorubicin 31Carboplatin 31Vinorelbine 30Bevacizumab 29Anastrozole 28pembrolizumab 25exemestane 24Tamoxifen 23Gemcitabine 22Radiotherapy 21Albumin-Bound Paclitaxel 19Everolimus 17Taxes 16Epirubicin 15Ado-Trastuzumab Emtansine 13130-nm albumin-bound paclitaxel 13pertuzumab 12palbociclib 12liposomal doxorubicin 11Magnetic Resonance Spectroscopy 11Filgrastim 11Cisplatin 11

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Terminated × Breast Neoplasms × Metformin × Clear all
NCT02874430 2026-04-22

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Thomas Jefferson University

Phase 2 Terminated
29 enrolled 11 charts
Breast

Breast Neoplasms

NCT00984490 2024-02-01

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Vanderbilt-Ingram Cancer Center

Phase NA Terminated
5 enrolled 4 charts
Breast

Breast Neoplasms

NCT01627067 2020-06-19

Exemestane-RAD001-Metformin

M.D. Anderson Cancer Center

Phase 2 Terminated
23 enrolled 7 charts
Breast

Breast Neoplasms

NCT02472353 2019-10-16

Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

Avera McKennan Hospital & University Health Center

Phase 2 Terminated
30 enrolled 10 charts
Breast

Breast Neoplasms, Neoplasms, Cardiotoxicity

NCT02360059 2017-08-17

Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer

M.D. Anderson Cancer Center

Phase 2 Terminated
1 enrolled 3 charts
Breast

Breast Neoplasms

NCT01477060 2014-02-20

Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer

Fondazione Michelangelo

Phase 2 Terminated
32 enrolled
Breast

Breast Neoplasms

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