Clinical Trials

Phase 1 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04052555 2026-05-13

Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer

42 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03488693 2026-05-12

TAILOR RT

Phase 3 Recruiting

2,140 enrolled

Breast Neoplasms

NCT04852887 2026-04-23

DEBRA

Phase 3 Recruiting

1,670 enrolled

Phase 1/2 Active not recruiting

Breast Neoplasms

NCT02917421 2026-04-17

ART

88 enrolled 10 charts

Breast Neoplasms

NCT01266642 2026-03-11

Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast Cancer

301 enrolled 9 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02927912 2026-02-17

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

108 enrolled

Breast Neoplasms

NCT04683679 2026-02-17

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

Phase 2 Recruiting

34 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT07188246 2026-02-11

BRINK

Phase 2 Recruiting

40 enrolled

Phase 1/2 Active not recruiting

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT04478279 2026-02-09

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

125 enrolled

BreastCNSDermatologicGenitourinary

Brain Neoplasms, Breast Neoplasms, Glioblastoma, Melanoma, Prostatic Neoplasms

NCT00066690 2026-02-06

SOFT

Phase 3 Completed

3,066 enrolled 15 charts

Breast Neoplasms

NCT02912312 2026-01-07

Hypofractionated vs. Conventional Regional Nodal Radiation Therapy for Patients With Invasive Breast Cancer

805 enrolled

Phase 1 Active not recruiting

Breast Neoplasms

NCT04616248 2026-01-07

In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors

14 enrolled

BreastDermatologicSarcoma

Bone Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Melanoma, Sarcoma, Osteosarcoma, Carcinoma, Merkel Cell

NCT06635980 2025-12-12

Hypofractionated Radiotherapy Before or After Breast Surgery for Treatment of Patients With Non-Metastatic Breast Cancer

Phase 2 Recruiting

120 enrolled

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01750073 2025-11-18

Paclitaxel & Cyclophosphamide With or Without Trastuzumab Before Surgery in Treating Previously Untreated Breast Cancer

92 enrolled 17 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01819233 2025-06-06

CAREFOR

38 enrolled 10 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT00838929 2025-05-04

Study of the Combination of Vorinostat and Radiation Therapy for the Treatment of Patients With Brain Metastases

17 enrolled 8 charts

BreastCNSThoracic

Brain Neoplasms, Breast Neoplasms, Lung Neoplasms

NCT03691493 2025-02-17

ASPIRE

36 enrolled 17 charts

Breast Neoplasms

NCT01618357 2024-05-22

Pre-Operative Radiation and Veliparib for Breast Cancer

19 enrolled

Breast Neoplasms

NCT03324802 2024-05-02

Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery

Phase 3 Completed

107 enrolled 17 charts

Breast Neoplasms

NCT06137651 2024-04-01

Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis

Phase 1 Withdrawn

BreastCNS

Brain Neoplasms, Breast Neoplasms, Meningeal Carcinomatosis

NCT03677427 2024-03-05

YO-HAI5

488 enrolled

Breast Neoplasms

NCT04756505 2023-12-27

Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial

Phase 1 Withdrawn

Breast Neoplasms

NCT04690855 2023-12-04

TARA

1 enrolled 11 charts

BreastDermatologicLymphoidSarcoma

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT02890368 2023-04-05

Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides

Phase 1 Terminated

56 enrolled

Breast Neoplasms, Carcinoma, Squamous Cell, Melanoma, Mycosis Fungoides, Sarcoma, Carcinoma, Merkel Cell

NCT03437161 2023-02-17

A Prospective Trial to Compare Deep Inspiratory Breath Hold (DIBH) With Prone Breast Irradiation

40 enrolled

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Deception

NCT00887523 2022-12-20

Trial Comparing Prone and Supine Intensity-modulated Radiotherapy (IMRT) After Breast-conserving Surgery in Patients With Large Breast Volume at High Risk for Skin Toxicity and Fibrosis

100 enrolled

Breast Neoplasms

NCT02335957 2022-04-01

OPTIMAL

489 enrolled

Breast Neoplasms

NCT03524170 2022-03-07

Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer

24 enrolled

Breast Neoplasms

NCT01727011 2021-12-17

SIFEBI

37 enrolled 7 charts

Breast Neoplasms

NCT01421017 2021-11-18

Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases

Phase 1/2 Completed

31 enrolled 11 charts

Breast Neoplasms

NCT03972696 2021-11-01

OPTIMALIIa

Phase NA Terminated

32 enrolled

Breast Neoplasms

NCT00278109 2020-02-19

Partial Breast Irradiation With Chemotherapy

Phase 1/2 Completed

27 enrolled 5 charts

Breast Neoplasms

NCT02538471 2019-12-09

LY2157299 Monohydrate (LY2157299) and Radiotherapy in Metastatic Breast Cancer

3 enrolled 11 charts

Breast Neoplasms

NCT00418210 2019-12-05

Accelerated Partial Breast Irradiation for Early Breast Cancer

48 enrolled

Breast Neoplasms

NCT02890316 2019-04-09

Assessment of Fatigue During Radiotherapy for Breast Cancer With and Without Homeopathy Treatment

64 enrolled

Breast Neoplasms

NCT01091883 2019-03-13

Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma

BreastGenitourinarySarcomaThoracic

60 enrolled

Cancer Pain, Bone Neoplasms, Breast Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Pain, Prostatic Neoplasms

NCT00376805 2017-12-28

Allogeneic Natural Killer (NK) Cells in Patients With Advanced Metastatic Breast Cancer

6 enrolled 9 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT02203565 2017-07-26

Dakin's Solution in Preventing Radiation Dermatitis in Patients With Breast Cancer Undergoing Radiation Therapy

20 enrolled 6 charts

Breast Neoplasms

NCT00003199 2017-07-12

Combination Chemotherapy and Peripheral Blood Stem Cell Transplant Followed By Aldesleukin and Sargramostim in Treating Patients With Inflammatory Stage IIIB or Metastatic Stage IV Breast Cancer

50 enrolled 11 charts

Breast Neoplasms, Breast Neoplasms, Male, Inflammatory Breast Neoplasms

NCT00194792 2017-07-11

Hormone Therapy and Combination Chemotherapy Before and After Surgery in Treating Patients With Stage I-IIIA Breast Cancer

28 enrolled 9 charts

Breast Neoplasms

NCT01754519 2017-07-07

Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery

1 enrolled 4 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01868503 2017-06-26

Lapatinib Ditosylate and Radiation Therapy in Treating Patients With Locally Advanced or Locally Recurrent Breast Cancer

7 enrolled 8 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00805597 2016-08-08

Clinical Trial of Postmastectomy Radiotherapy in Breast Cancer With One to Three Positive Nodes

Phase 3 Terminated

40 enrolled

Breast Neoplasms

NCT00119262 2014-05-15

Bevacizumab and Combination Chemotherapy in Patients With Lymph Node Positive Breast Cancer

226 enrolled 8 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00724386 2014-03-07

Concomitant Chemoradiotherapy With Weekly Paclitaxel and Vinorelbine and Granulocyte Colony Stimulating Factor (GCSF) Support in Patients With Advanced Breast Cancer

26 enrolled

Breast Neoplasms

NCT00016276 2013-01-16

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

Phase 3 Terminated

396 enrolled