Announcements Trials
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Phase

Phase 2 2Phase NA 1Phase 3 1

Status

Recruiting 4Completed 1Active not recruiting 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4CNS 4Breast 4

Conditions

Burkitt Lymphoma 7Meningeal Carcinomatosis 5Lung Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Breast Neoplasms 4Leukemia, Myeloid, Acute 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Meningeal Neoplasms 2Lymphoma, Large B-Cell, Diffuse 2Uveal Melanoma 1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 1Nevus 1Melanoma 1Lymphoma, T-Cell 1Lymphoma, Mantle-Cell 1Leukemia, Myelomonocytic, Juvenile 1Leukemia, Monocytic, Acute 1Leukemia, Hairy Cell 1Leukemia, Biphenotypic, Acute 1Hematopoietic and Lymphatic System Neoplasm 1Germinoma 1Down Syndrome 1Diabetes Insipidus 1Brain Neoplasms 1

Interventions

Fulvestrant 58Trastuzumab 49Capecitabine 48Letrozole 45pembrolizumab 41Carboplatin 41Paclitaxel 39Cyclophosphamide 38ribociclib 37pertuzumab 36abemaciclib 36Blood Specimen Collection 31Specimen Handling 28trastuzumab deruxtecan 27Docetaxel 27Surveys and Questionnaires 26Anastrozole 25exemestane 24Tamoxifen 24palbociclib 21130-nm albumin-bound paclitaxel 21Magnetic Resonance Spectroscopy 20Biopsy 19sacituzumab govitecan 18eribulin 18Radiotherapy 18Gemcitabine 18olaparib 17Injections 17Epirubicin 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Recruiting × Breast Neoplasms × Spinal Puncture × Clear all
NCT06500481 2026-05-07

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

NRG Oncology

Phase 3 Recruiting
115 enrolled
BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Carcinomatosis

NCT05746325 2026-04-02

Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer

Mayo Clinic

Phase NA Recruiting
5 enrolled
BreastCNSThoracic

Breast Neoplasms, Lung Neoplasms, Meningeal Carcinomatosis

NCT06518057 2025-12-11

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

University of Washington

Phase 2 Recruiting
22 enrolled
BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Carcinomatosis

NCT06910761 2025-12-08

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

City of Hope Medical Center

Phase 2 Recruiting
35 enrolled
BreastCNSThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Meningeal Carcinomatosis

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