Announcements Trials
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Phase

Phase 2 2Phase 1 2Phase 1/2 1

Status

Completed 4Terminated 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Breast 5

Conditions

Breast Neoplasms 5Colorectal Neoplasms 4Carcinoma, Non-Small-Cell Lung 4Neoplasms 3Lung Neoplasms 3Solid Tumors 1Rectal Neoplasms 1Pleural Effusion 1Pancreatic Neoplasms 1Ovarian Neoplasms 1Neuroendocrine Tumors 1Neoplasm Metastasis 1Multiple Myeloma 1Insulin-Like Growth Factor I, Resistance To 1Fallopian Tube Neoplasms 1Advanced Solid Tumors 1Adenocarcinoma 1

Interventions

Trastuzumab 597Paclitaxel 562Cyclophosphamide 545Docetaxel 479Capecitabine 388Letrozole 350Fulvestrant 311Doxorubicin 285Carboplatin 277Tamoxifen 257Anastrozole 219exemestane 211Epirubicin 210Radiotherapy 197Bevacizumab 189pertuzumab 177Gemcitabine 163Vinorelbine 162pembrolizumab 161Lapatinib 161palbociclib 152Exercise 132Fluorouracil 118Albumin-Bound Paclitaxel 116eribulin 108Magnetic Resonance Spectroscopy 108130-nm albumin-bound paclitaxel 107Everolimus 103Taxes 96Cisplatin 92

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Breast Neoplasms × dalotuzumab × Clear all
NCT01605396 2019-03-25

MK-8669-064

Merck Sharp & Dohme LLC

Phase 2 Completed
80 enrolled 13 charts
Breast

Breast Neoplasms

NCT00759785 2018-08-15

MK-0646-013

Merck Sharp & Dohme LLC

Phase 1 Completed
48 enrolled 10 charts
Breast

Breast Neoplasms

NCT01234857 2017-05-31

A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3)

Merck Sharp & Dohme LLC

Phase 2 Completed
115 enrolled
Breast

Breast Neoplasms

NCT00903006 2015-02-02

Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast Cancer

M.D. Anderson Cancer Center

Phase 1/2 Terminated
11 enrolled 6 charts
Breast

Breast Neoplasms

NCT01220570 2015-01-21

The Growth Factor Signature (GFS) as an Intermediate Biomarker of Response for Development of PI3K-Pathway Inhibitors in Patients With Breast Cancer (MK-8669-050)

Merck Sharp & Dohme LLC

Phase 1 Completed
63 enrolled
Breast

Breast Neoplasms

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