Clinical Trials Browser

Phase 2 × Breast Neoplasms × trastuzumab deruxtecan × Clear all

NCT07619365 2026-06-02

Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer

Phase 2 Not yet recruiting

Breast Neoplasms

NCT06271837 2026-05-11

A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors

Phase 2 Active not recruiting

Breast Neoplasms

NCT06048718 2026-05-08

TUXEDO-4

Phase 2 Active not recruiting

Brain Neoplasms, Breast Neoplasms

NCT06172127 2026-04-29

DEMETHER

Phase 2 Active not recruiting

Breast Neoplasms

NCT05744375 2026-04-02

TRANSCENDER

Phase 2 Terminated

2 enrolled 10 charts

Breast Neoplasms

NCT07371585 2026-03-27

TOP-REAL

Phase 2 Recruiting

Breast Neoplasms

NCT04539938 2026-03-23

HER2CLIMB-04

Phase 2 Completed

70 enrolled 23 charts

Breast Neoplasms

NCT07416253 2026-02-18

Trastuzumab Rezetecan vs Trastuzumab Deruxtecan in the Neoadjuvant Treatment of HER2 Positive Breast Cancer

Phase 2 Not yet recruiting

Breast Neoplasms

NCT07393425 2026-02-06

Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer

Phase 2 Recruiting

Breast Neoplasms

NCT07368543 2026-01-28

STORM

Phase 2 Not yet recruiting

Breast Neoplasms

NCT06409390 2025-12-04

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

Phase 2 Recruiting

Breast Neoplasms

NCT04986579 2025-11-19

Scalp Cooling in MBC

Phase 2 Recruiting

Breast Neoplasms

NCT04553770 2025-11-10

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Phase 2 Recruiting

Breast Neoplasms

NCT06533826 2025-10-24

TRADE DXd

Phase 2 Recruiting

Breast Neoplasms

NCT05795101 2025-09-19

TRUDI

Phase 2 Recruiting

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT07151586 2025-09-03

ALTER

Phase 2 Not yet recruiting

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT05900206 2025-09-02

ARIADNE

Phase 2 Recruiting

Breast Neoplasms

NCT03248492 2025-06-26

DESTINY-Breast01

Phase 2 Terminated

253 enrolled 21 charts 1 FDA

Breast Neoplasms, Neoplasm Metastasis

NCT06439693 2025-06-26

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Phase 2 Recruiting

Breast Neoplasms

NCT04420598 2025-06-24

DEBBRAH

Phase 2 Completed

41 enrolled 32 charts

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Meningeal Carcinomatosis

NCT04132960 2025-06-12

DAISY

Phase 2 Completed

Breast Neoplasms

NCT06797622 2025-01-28

Heterogeneity of 68Ga-FAPI Uptake As Imaging Biomarker in T-DXd Treatment for Brain Metastasis of HER2 Positive Breast Cancer

Phase 2 Not yet recruiting

Breast Neoplasms

NCT04752059 2023-05-12

TUXEDO-1

Phase 2 Completed

Breast Neoplasms