Announcements Trials
Browse Landscape

Phase

Phase 2 3Phase 3 1Phase 1/2 1Phase 1 1

Status

Recruiting 11Completed 7Active not recruiting 6Withdrawn 4Terminated 4Not yet recruiting 1No longer available 1

Sponsor Class

INDUSTRY 5OTHER 1

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 6Gastrointestinal 2Thoracic 1Gynecologic 1Genitourinary 1CNS 1

Conditions

Breast Neoplasms 6Colorectal Neoplasms 3Brain Neoplasms 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urologic Neoplasms 1Stomach Neoplasms 1Metastatic Breast Cancer With a Isolated Brain Progression 1HER2-positive Metastatic Breast Cancer 1HER2-positive Gastric Cancer 1HER2-positive Breast Cancer 1Gallbladder Neoplasms 1Esophageal Neoplasms 1Cholangiocarcinoma 1Carcinoma, Non-Small-Cell Lung 1Biliary Tract Neoplasms 1Anatomic Stage II Breast Cancer AJCC v8 1Anatomic Stage IA Breast Cancer AJCC v8 1Adenocarcinoma Of Esophagus 1

Interventions

Paclitaxel 62Letrozole 55Fulvestrant 55Trastuzumab 50palbociclib 41pembrolizumab 37Cyclophosphamide 37Carboplatin 37Anastrozole 37pertuzumab 35exemestane 25Tamoxifen 24Capecitabine 24ribociclib 23abemaciclib 23Radiotherapy 21Docetaxel 21olaparib 20Doxorubicin 20Magnetic Resonance Spectroscopy 19trastuzumab deruxtecan 17Surveys and Questionnaires 17durvalumab 16Epirubicin 16Specimen Handling 14Exercise 14130-nm albumin-bound paclitaxel 14Taxes 13Alpelisib 13Goserelin 12

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Active not recruiting × Breast Neoplasms × tucatinib × Clear all
NCT05132582 2026-04-20

HER2CLIMB-05

Seagen Inc.

Phase 3 Active not recruiting
654 enrolled
Breast

Breast Neoplasms

NCT05382364 2026-03-12

Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)

Pfizer

Phase 1 Active not recruiting
25 enrolled
BreastGastrointestinal

Breast Neoplasms, Colorectal Neoplasms

NCT05892068 2026-02-13

A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
9 enrolled
Breast

Breast Neoplasms

NCT04721977 2026-01-09

MK-7119-001

Pfizer

Phase 2 Active not recruiting
66 enrolled 7 charts
Breast

Breast Neoplasms

NCT04579380 2025-12-19

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Seagen Inc.

Phase 2 Active not recruiting
217 enrolled 19 charts
BreastGastrointestinalGenitourinaryGynecologicThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Urologic Neoplasms, Uterine Neoplasms, Colorectal Neoplasms

NCT04538742 2025-12-08

DB-07

AstraZeneca

Phase 1/2 Active not recruiting
245 enrolled
BreastCNS

Brain Neoplasms, Breast Neoplasms

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