Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Recruiting 1Completed 1

Sponsor Class

OTHER 31INDUSTRY 5OTHER_GOV 3NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2

Conditions

Melanoma 27Neoplasm Metastasis 16Skin Neoplasms 12Breast Neoplasms 9Multiple Myeloma 8Kidney Neoplasms 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 7Pancreatic Neoplasms 7Ovarian Neoplasms 7Lymphoma 7Leukemia, Lymphocytic, Chronic, B-Cell 7Leukemia 7Hematologic Neoplasms 7Neoplasms 6Myelodysplastic Syndromes 6Leukemia, Myeloid, Acute 6Uterine Cervical Neoplasms 5Lymphoma, Non-Hodgkin 5Lymphoma, B-Cell 5Carcinoma, Non-Small-Cell Lung 5Urogenital Neoplasms 4Stomach Neoplasms 3Lung Neoplasms 3Liver Neoplasms 3Gastrointestinal Neoplasms 3Colorectal Neoplasms 3Colonic Neoplasms 3Carcinoma, Renal Cell 3Vaginal Neoplasms 2Rectal Neoplasms 2

Interventions

Cyclophosphamide 30Vincristine 22Rituximab 19Etoposide 19Prednisone 18Filgrastim 16Doxorubicin 16Cytarabine 16Methotrexate 15Radiotherapy 14Peripheral Blood Stem Cell Transplantation 13merphos 11Leucovorin 11blinatumomab 10N,N-dicyclohexyl-isoborneol-10-sulfonamide 10Mercaptopurine 10Dexamethasone 10azathiopurine 9Specimen Handling 9Methylprednisolone 9Calcium Dobesilate 9Biopsy 9dexamethasone acetate 8dexamethasone 21-phosphate 8auricularum 8Cyclosporine 8prednylidene 7pegaspargase 7fludarabine phosphate 7deltacortene 7

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Burkitt Lymphoma × fludarabine × Clear all
NCT05442515 2026-05-28

CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1/2 Recruiting
130 enrolled
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03448393 2025-06-04

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
54 enrolled 24 charts
LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Lymphoma, Lymphoma, Non-Hodgkin, Philadelphia Chromosome, Leukemia, B-Cell, Lymphoma, B-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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