Clinical Trials
35 trialsNCT06989437 2026-05-20
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Pfizer
Phase 2/3 Recruiting
NCT07112196 2026-05-20
VINCIT
CatalYm GmbH
Phase 2/3 Recruiting
NCT06736275 2026-05-15
A Phase I Study on Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of SXRN Plasmid DNA Technique in Patients With Advanced Solid Tumors
Jiangsu Nutai Biologics Co., Ltd
Phase EARLY_PHASE1 Recruiting
NCT06937177 2026-05-11
Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy
Endevica Bio
Phase 2 Recruiting
NCT07530666 2026-04-15
Study of the Safety and Efficacy of DS010 in Patients With Cancer Cachexia
Dartsbio Pharmaceuticals Ltd.
Phase 1/2 Not yet recruiting
NCT07519564 2026-04-09
A Phase I Clinical Study to Evaluate the PK, PD, Efficacy, and Safety of GB18 Injection in Patients With Tumor Cachexia
Kexing Biopharm Co., Ltd.
Phase 1 Not yet recruiting
NCT07356037 2026-01-21
Nanocrystalline Megestrol Acetate for Cachectic Stage Locally Advanced Hepatocellular Carcinoma
Changchun GeneScience Pharmaceutical Co., Ltd.
Phase 3 Not yet recruiting
NCT05865535 2026-01-08
A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia
AVEO Pharmaceuticals, Inc.
Phase 1 Recruiting
NCT07168226 2025-09-11
Phase 2 Cachexia Clinical Trial to Evaluate the Efficacy and Safety of ASCA101
MetaFines
Phase 2 Not yet recruiting
NCT06898255 2025-06-05
A Phase I Study to Evaluate GFS202A in Advanced Solid Tumor Patients With Pre-cachexia or Cachexia
Genfleet Therapeutics (Shanghai) Inc.
Phase 1 Recruiting
NCT05546476 2025-05-31
PROACC-1
Pfizer
Phase 2 Completed
NCT06940102 2025-04-23
Real-World Study on Nano-Crystalline Megestrol Acetate for Cachexia in TKI-Treated Advanced Digestive Tumors
Changchun GeneScience Pharmaceutical Co., Ltd.
Recruiting
NCT03743051 2024-06-26
A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Helsinn Healthcare SA
Phase 3 Completed
NCT03743064 2024-06-26
A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Helsinn Healthcare SA
Phase 3 Completed
NCT04803305 2024-01-12
Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia
Pfizer
Phase 1 Completed
NCT04299048 2023-12-14
Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia.
Pfizer
Phase 1 Completed
NCT04001010 2021-02-05
SERENITY
Tetra Bio-Pharma
Phase 3 Suspended
NCT00866970 2020-07-09
Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia
CSL Behring
Phase 2 Completed
NCT02968979 2019-09-24
CacheMire
Chugai Pharma France
Completed
NCT01387269 2017-10-27
Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)
Helsinn Therapeutics (U.S.), Inc
Phase 3 Completed
NCT01387282 2017-10-27
Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2)
Helsinn Therapeutics (U.S.), Inc
Phase 3 Completed
NCT01395914 2017-09-14
Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3)
Helsinn Therapeutics (U.S.), Inc
Phase 3 Completed
NCT02515032 2017-07-17
Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia
Smartfish AS
Phase NA Completed
NCT00637728 2016-06-23
Treatment of Cancer-anorexia Using Megestrol Acetate Concentrated Suspension in Lung or Pancreatic Cancer Patients
Par Pharmaceutical, Inc.
Phase 3 Terminated
NCT00637806 2016-05-02
Treatment of Cancer-associated Anorexia Using Megestrol Acetate Concentrated Suspension
Par Pharmaceutical, Inc.
Phase 3 Terminated
NCT01433263 2016-03-02
Clinical Study of BYM338 for the Treatment of Unintentional Weight Loss in Patients With Cancer of the Lung or the Pancreas
Novartis
Phase 2 Completed
NCT01046383 2015-01-21
Effect of IMN1207 Versus Casein on Weight Loss, Survival and Quality of Life in Non-small Cell Lung Cancer Patients
Immunotec Inc.
Phase 3 Terminated
NCT01238107 2014-09-10
A Clinical Study With MT-102 in Subjects With Cancer Cachexia
Akamis Bio
Phase 2 Completed
NCT00467844 2014-07-11
Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.
GTx
Phase 2 Completed
NCT00219817 2013-09-02
Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss
Helsinn Therapeutics (U.S.), Inc
Phase 2 Completed
NCT00527319 2013-01-30
VT-122
Vicus Therapeutics
Phase 2 Completed
NCT00895726 2012-01-13
Pilot Study of APD209 in Cancer Cachexia
Acacia Pharma Ltd
Phase 2 Completed
NCT00851448 2011-06-02
Safety, Tolerance and Efficacy of an Oral Nutritional Supplement in Lung Cancer Patients
Fresenius Kabi
Phase NA Terminated
NCT00060502 2011-05-17
A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Pancreatic Cancer Related Cachexia
Centocor, Inc.
Phase 2 Completed
NCT00535015 2008-07-22
Safety and Efficacy Study of Betamarc to Treat Loss of Weight and Appetite in Non-Small Cell Lung Cancer
Anaborex
Phase 2 Terminated