Clinical Trials

Phase 2 Not yet recruiting

Carcinoma, Basal Cell, Skin Neoplasms

NCT07227870 2026-03-09

L19IL2/TNF in Patients With Basal Cell Carcinoma

92 enrolled

Phase 2 Active not recruiting

Carcinoma, Basal Cell

NCT06422936 2026-01-26

SPOTLIGHT204

60 enrolled

Carcinoma, Basal Cell

NCT03889912 2026-01-21

Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma

97 enrolled

Carcinoma, Basal Cell

NCT03886181 2025-12-08

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal and Superficial Soft Tissue Neoplasia (DaRT)

Phase NA Terminated

2 enrolled

BreastDermatologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04916002 2025-12-05

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Phase 2 Terminated

77 enrolled 18 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Carcinoma, Merkel Cell, Triple Negative Breast Neoplasms

NCT03889899 2025-12-02

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia.

Phase NA Recruiting

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04540588 2025-12-02

Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

Phase NA Completed

2 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Recurrence, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04272034 2025-10-16

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Phase 1 Terminated

105 enrolled

Nasopharyngeal Carcinoma, Esophageal Squamous Cell Carcinoma, Anus Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Mesothelioma, Neoplasm Metastasis, Carcinoma, Merkel Cell, Endometrial Neoplasms, Small Cell Lung Carcinoma

NCT06880848 2025-09-24

Sonidegib in Adult Patients With Locally Advanced Basal Cell Carcinoma (laBCC) in China

Phase 4 Completed

160 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Carcinoma, Carcinoma, Basal Cell

NCT05086692 2025-07-09

ABILITY-1

Phase 1/2 Recruiting

115 enrolled

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Mesothelioma, Malignant, Urinary Bladder Neoplasms, Carcinoma, Basal Cell, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Fallopian Tube Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Skin Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT05592626 2025-07-09

START-001

Phase 1/2 Recruiting

365 enrolled

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Abdominal Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Esophageal Neoplasms, Gastrointestinal Neoplasms, Genital Neoplasms, Female, Head and Neck Neoplasms, Lung Neoplasms, Melanoma, Nasopharyngeal Neoplasms, Neoplasms, Neoplasms by Site, Stomach Neoplasms, Urogenital Neoplasms, Vulvar Diseases, Vulvar Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Endometrial Neoplasms, Epstein-Barr Virus Infections, Papillomavirus Infections, Microsatellite Instability, Small Cell Lung Carcinoma

NCT05188729 2025-06-18

Open-Label Proof of Concept Study of VP-315 in Basal Cell Carcinoma

92 enrolled 17 charts

Carcinoma, Carcinoma, Basal Cell, Neoplasms, Skin Neoplasms

NCT03897036 2025-05-20

Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC)

25 enrolled 9 charts

Carcinoma, Basal Cell

NCT00472459 2025-04-18

Photodynamic Therapy (PDT) With Metvix® 160 Milligrams/Gram Cream in Organ Transplant Participants With Non-melanoma Skin Cancer

82 enrolled 20 charts

Bowen's Disease, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Warts, Keratosis, Actinic

NCT03132636 2025-04-08

PD-1 in Patients With Advanced Basal Cell Carcinoma Who Experienced Progression of Disease on Hedgehog Pathway Inhibitor Therapy, or Were Intolerant of Prior Hedgehog Pathway Inhibitor Therapy

138 enrolled 21 charts 1 FDA

Carcinoma, Basal Cell

NCT04534127 2025-02-07

Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia

Phase NA Recruiting

56 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Lip Neoplasms, Sarcoma, Kaposi, Skin Neoplasms, Soft Tissue Neoplasms, Tongue Neoplasms

NCT04470726 2024-12-27

NMSC

Phase 1/2 Completed

26 enrolled

Carcinoma, Basal Cell

NCT04068155 2024-11-22

Alpha Radiation Emitters Device for the Treatment of of Malignant Cutaneous Tumors

Phase NA Recruiting

80 enrolled

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Eyelid Neoplasms, Lip Neoplasms, Skin Neoplasms

NCT04308395 2024-09-24

Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)

Phase 3 Terminated

108 enrolled 12 charts

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT06344052 2024-09-20

To Assess the Safety and Efficacy of SP-002 with Vismodegib for the Treatment of Locally Advanced Basal Cell Carcinoma

Phase 2 Recruiting

80 enrolled

Carcinoma, Basal Cell

NCT04893486 2024-08-29

CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome

73 enrolled

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT00472043 2024-08-06

PDT With Metvix 160 mg/g Cream Versus PDT With Placebo Cream in Participants With Primary Nodular Basal Call Carcinoma

66 enrolled 15 charts

Carcinoma, Basal Cell

NCT00472108 2024-08-05

Photodynamic Therapy (PDT) With Metvix Cream 160 mg/g Versus PDT With Placebo Cream in Participants With Primary Nodular Basal Cell Carcinoma

65 enrolled 15 charts

Carcinoma, Basal Cell

NCT04925713 2024-08-02

IFx-Hu2.0 for the Treatment of Patients With Skin Cancer

5 enrolled 6 charts

Carcinoma, Basal Cell, Neoplasms

NCT03703310 2024-07-03

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

174 enrolled 23 charts

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT04416516 2024-04-10

Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor

21 enrolled

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT04669808 2024-03-18

Open Label, Dose Escalation Study for the Safety and Efficacy of STP705 in Adult Patients With Basal Cell Carcinoma

32 enrolled

Carcinoma, Basal Cell

NCT06271603 2024-02-22

ECOBASO

Phase NA Unknown

704 enrolled

Carcinoma, Basal Cell

NCT04362722 2023-10-10

DUNCAN

Phase 2 Unknown

40 enrolled

Carcinoma, Carcinoma, Basal Cell

NCT05329792 2023-10-06

IntriNSiC

Phase 2 Unknown

70 enrolled

DermatologicSarcoma

Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Sarcoma, Kaposi, Carcinoma, Merkel Cell

NCT04155190 2023-05-31

An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Phase 2 Terminated

47 enrolled

Phase 1/2 Active not recruiting

Rombo syndrome, Basal Cell Nevus Syndrome, Carcinoma, Basal Cell, Syndrome, Xeroderma Pigmentosum

NCT04928222 2023-04-14

Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II)

25 enrolled

Carcinoma, Basal Cell, Neoplasms, Basal Cell

NCT03208296 2023-02-06

Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)

Phase 1/2 Suspended

24 enrolled

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT04918381 2023-01-11

CellFX Treat & Resect Low-Risk BCC Feasibility Study

Phase NA Completed

30 enrolled 6 charts

Margins of Excision, Carcinoma, Basal Cell

NCT00473343 2023-01-05

Metvix PDT in Participant With "High Risk" Basal Cell Carcinoma

102 enrolled 13 charts

BreastDermatologicGastrointestinalHead & NeckLymphoidSarcoma

Carcinoma, Basal Cell

NCT03775525 2022-12-23

GEN602

Phase 1 Unknown

127 enrolled

Squamous Cell Carcinoma of Head and Neck, Breast Neoplasms, Carcinoma, Basal Cell, Colonic Neoplasms, Lymphoma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Lymphoma, T-Cell, Cutaneous

NCT04936932 2022-12-08

Laser Treatment of Basal Cell Carcinoma

Phase NA Completed

3 enrolled

Carcinoma, Basal Cell

NCT03517488 2022-12-01

DUET-2

BreastDermatologicEndocrineGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

150 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Anus Neoplasms, Bile Duct Neoplasms, Breast Neoplasms, Carcinoma, Basal Cell, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Melanoma, Mesothelioma, Nasopharyngeal Neoplasms, Ovarian Neoplasms, Penile Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Stomach Neoplasms, Thymoma, Thymus Neoplasms, Vulvar Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Carcinoma, Neuroendocrine, Cholangiocarcinoma, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT02144077 2022-11-03

Safety and Efficacy Study for the Treatment of Non-Aggressive Basal Cell Carcinoma With Photodynamic Therapy

281 enrolled 16 charts

Carcinoma, Basal Cell

NCT00189280 2022-02-22

Aldara for the Treatment of Large and/or Multiple sBCC

111 enrolled