Clinical Trials

Phase NA Active not recruiting

Carcinoma, Intraductal, Noninfiltrating

NCT02926911 2026-05-12

COMET

997 enrolled 16 charts

Phase 1 Active not recruiting

Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal

NCT03317405 2026-05-04

Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

32 enrolled 12 charts

Phase 3 Active not recruiting

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01905046 2026-04-28

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

86 enrolled 10 charts

Phase 2 Active not recruiting

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT01266642 2026-03-11

Hypofractionated Radiation Therapy or Standard Radiation Therapy in Treating Patients With Ductal Breast Carcinoma In Situ or Early Invasive Breast Cancer

301 enrolled 9 charts

Phase 3 Active not recruiting

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01349322 2026-03-05

Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery

2,354 enrolled 29 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03345420 2025-12-30

NOVEMBER

102 enrolled 12 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00556907 2025-11-06

Targeted Intra-Operative Radiotherapy for the Management of Ductal Carcinoma In-Situ of the Breast

Phase NA Terminated

36 enrolled 6 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03535506 2025-09-26

WI223281

17 enrolled 9 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01841749 2025-09-12

CINNAMOME

228 enrolled 4 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00769379 2025-06-12

Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy

2,014 enrolled 16 charts

Carcinoma, Intraductal, Noninfiltrating

NCT01819233 2025-06-06

CAREFOR

38 enrolled 10 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT05086705 2025-04-22

EMBr Wave for the Reduction of Hot Flashes in Women With a History of Breast Cancer

50 enrolled 8 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Hot Flashes

NCT02993159 2024-12-18

Testing an Active Form of Tamoxifen (4-hydroxytamoxifen) Delivered Through Breast Skin to Control Ductal Carcinoma in Situ (DCIS) of the Breast

100 enrolled 15 charts

Carcinoma, Intraductal, Noninfiltrating

NCT00072462 2024-09-19

IBIS-II DCIS

2,980 enrolled 14 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02876640 2024-06-18

Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer

Phase 1 Terminated

27 enrolled 21 charts

Carcinoma, Intraductal, Noninfiltrating

NCT02636582 2023-12-05

Nelipepimut-S Plus GM-CSF Vaccine Therapy in Treating Patients With Breast Cancer

43 enrolled 10 charts

Carcinoma, Intraductal, Noninfiltrating

NCT01556243 2023-11-30

Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer

270 enrolled 11 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02127073 2023-11-09

Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer

8 enrolled 5 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02526498 2023-05-15

TRIUMPH-T

200 enrolled 7 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02314156 2023-02-22

Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy

67 enrolled 14 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT03775213 2023-01-30

Acceptability of Active Monitoring (AM) as a Treatment Option for Ductal Carcinoma in Situ (DCIS)

322 enrolled 14 charts

Carcinoma, Intraductal, Noninfiltrating

NCT03323658 2023-01-10

Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer

Phase 1 Completed

24 enrolled 12 charts

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating

NCT01082211 2022-06-21

Radiation Therapy in Treating Women With Locally Recurrent Breast Cancer Previously Treated With Repeat Breast-Preserving Surgery

65 enrolled 16 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT01961531 2022-03-04

BrUOG 291: Five Fraction Partial Breast Irradiation Using Non-invasive Image-guided Breast Brachytherapy (NIBB)

40 enrolled 8 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01849250 2021-12-28

Study of Docosahexaenoic Acid (DHA) in Triple Negative Breast Cancer Survivors

65 enrolled 11 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Paget's Disease, Mammary

NCT02137252 2021-11-16

Naltrexone RCT for Treatment-Emergent Fatigue in Patients Receiving Radiation Therapy for Breast Cancer

3 enrolled 4 charts

Breast Carcinoma In Situ, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Lobular

NCT00110136 2021-09-29

St. John's Wort in Relieving Hot Flashes in Postmenopausal Women With Non-Metastatic Breast Cancer

9 enrolled 10 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Hot Flashes

NCT01448447 2021-07-15

Mammosite ML

20 enrolled 3 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01023477 2021-06-29

Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial)

Phase 1/2 Completed

12 enrolled 10 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00256217 2021-05-11

Chemoprevention Trial - Anastrozole in Ductal Carcinoma In Situ (DCIS) in Postmenopausal Women

42 enrolled 10 charts

Carcinoma, Intraductal, Noninfiltrating

NCT00290745 2020-12-04

Tamoxifen or Letrozole in Treating Women With Ductal Carcinoma in Situ

Phase 1/2 Completed

79 enrolled 15 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00496808 2020-09-23

Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast

69 enrolled 6 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00945061 2020-08-18

Radiation Therapy in Treating Patients With Recurrent Breast Cancer

13 enrolled 43 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Breast Neoplasms, Male

NCT01060345 2020-04-09

A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ

20 enrolled 5 charts

Carcinoma, Intraductal, Noninfiltrating

NCT03505372 2020-02-11

Role of Contrast Enhanced Spectral Mammography to Predict Upgrade Rates of Biopsy Proven Atypical Ductal Hyperplasia

Phase NA Terminated

5 enrolled 4 charts

Carcinoma, Intraductal, Noninfiltrating

NCT02961790 2020-01-18

Oxybutynin Chloride in Managing Hot Flashes

150 enrolled 16 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Hot Flashes

NCT01869764 2019-10-30

Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast Cancer

57 enrolled 8 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Breast Neoplasms, Male

NCT02248662 2019-09-06

Impact of Radiation Therapy on Breast Conservation in DCIS

3,436 enrolled 20 charts

Carcinoma, Intraductal, Noninfiltrating, Neoplasms

NCT02216136 2019-08-02

T:B

162 enrolled 6 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00058058 2019-07-16

ACRIN-6667

1,007 enrolled 9 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT02908178 2019-05-15

Comparative Effectiveness of Sentinel Lymph Node Biopsy for Ductal Carcinoma In Situ

28,291 enrolled 26 charts

Carcinoma, Intraductal, Noninfiltrating

NCT00334542 2019-04-03

Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer

50 enrolled 6 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00053898 2018-09-20

Anastrozole or Tamoxifen in Treating Postmenopausal Women With Ductal Carcinoma in Situ Who Are Undergoing Lumpectomy and Radiation Therapy

3,104 enrolled 16 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01194440 2018-09-12

Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms

63 enrolled 7 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00555152 2018-04-20

Lapatinib Ditosylate in Treating Patients With Ductal Breast Carcinoma In Situ

22 enrolled 9 charts

Carcinoma, Intraductal, Noninfiltrating

NCT02365714 2018-04-13

CK-SAPBI

Phase 1/2 Terminated

2 enrolled 5 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00090857 2018-03-30

WISE

49 enrolled 17 charts

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT01439711 2018-03-27

Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in Situ

108 enrolled 13 charts

Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT00290654 2017-12-28

Internal Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ

45 enrolled 11 charts