Announcements Trials
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Phase

Phase 2 2Phase 3 1

Status

Terminated 1Completed 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Gastrointestinal 1Breast 1

Conditions

Breast Neoplasms 145Neoplasm Metastasis 16Advanced Breast Cancer 9Neoplasms 8Ovarian Neoplasms 6Carcinoma, Non-Small-Cell Lung 6Breast Cancer Metastatic 5Prostatic Neoplasms 4Endometrial Neoplasms 4Recurrence 3Hereditary Sensory and Autonomic Neuropathies 3Lung Neoplasms 2Hyperglycemia 2Exanthema 2Estrogen Receptor-positive Breast Cancer 2Colorectal Neoplasms 2Carcinoma, Lobular 2Breast Neoplasms, Male 2Uterine Neoplasms 1Uterine Cervical Neoplasms 1Urologic Neoplasms 1Triple Negative Breast Neoplasms 1Stomach Neoplasms 1Squamous Cell Carcinoma of Head and Neck 1Small Cell Lung Carcinoma 1Sex Cord-Gonadal Stromal Tumors 1Sarcoma, Endometrial Stromal 1Salivary Gland Neoplasms 1Recurrent Uterine Corpus Carcinoma 1Neoplastic Cells, Circulating 1

Interventions

Carboplatin 4Trastuzumab 3Cyclophosphamide 3Paclitaxel 2Letrozole 2Fulvestrant 2Docetaxel 2repotrectinib 1proto-oncogene protein c-fes-fps 1palbociclib 1neratinib 1entrectinib 1Vorinostat 1Vinorelbine 1Thiotepa 1Taxes 1Tamoxifen 1Sugars 1Radiotherapy 1Positron Emission Tomography Computed Tomography 1Neoadjuvant Therapy 1Naltrexone 1Melphalan 1Mastectomy, Segmental 1Magnetic Resonance Spectroscopy 1Liquid Biopsy 1High-Energy Shock Waves 1Goserelin 1Fluorine-18 1Epirubicin 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Carcinoma, Lobular × Fulvestrant × Clear all
NCT06408168 2026-01-05

Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)

M.D. Anderson Cancer Center

Phase 2 Terminated
6 enrolled

Carcinoma, Lobular

NCT03620643 2025-10-30

ROLo

Royal Marsden NHS Foundation Trust

Phase 2 Completed
33 enrolled 13 charts
BreastGastrointestinal

Stomach Neoplasms, Carcinoma, Lobular, Triple Negative Breast Neoplasms

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